Gpr151 G protein-coupled receptor 151 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpr151provided by RGD
Official Full Name: G protein-coupled receptor 151provided by RGD
Primary source: RGD:727873
See related: EnsemblRapid:ENSRNOG00000027103 AllianceGenome:RGD:727873
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: nGPCR-2037
Summary: Predicted to enable identical protein binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; regulation of synaptic vesicle exocytosis; and response to acidic pH. Predicted to be active in cholinergic synapse; presynaptic membrane; and synaptic vesicle membrane. Orthologous to human GPR151 (G protein-coupled receptor 151). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 18p11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (34819878..34821272, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (34568907..34570301, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (36892403..36893797, complement)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study demonstrated that GPR151 expression in the rats brain is restricted to habenular neurons projecting to the interpeduncular nucleus,Rostromedial tegmental nucleus, rhabdoid nucleus, mesencephalic raphe nuclei, and dorsal tegmental nucleus.
Title: Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates.

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in neuropeptide signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in regulation of synaptic vesicle exocytosis	ISO Inferred from Sequence Orthology more info
involved_in response to acidic pH	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cholinergic synapse	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic membrane	ISO Inferred from Sequence Orthology more info
is_active_in synaptic vesicle membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: probable G-protein coupled receptor 151

Names: GPCR-2037; putative G protein-coupled receptor nGPCR-2037

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.