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    Snx22 sorting nexin 22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300796, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snx22provided by RGD
    Official Full Name
    sorting nexin 22provided by RGD
    Primary source
    RGD:1305042
    See related
    EnsemblRapid:ENSRNOG00000022852 AllianceGenome:RGD:1305042
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be located in membrane. Orthologous to human SNX22 (sorting nexin 22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 197.5), Spleen (RPKM 158.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snx22 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (75503297..75509271, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (66609914..66612932, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (71725405..71728729, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor interactor 4 Neighboring gene U6 spliceosomal RNA Neighboring gene PCNA clamp associated factor Neighboring gene casein kinase 1, gamma 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene peptidylprolyl isomerase B Neighboring gene sorting nexin 1 Neighboring gene cytosolic iron-sulfur assembly component 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106832.2 → NP_001100302.2  sorting nexin-22

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      Related
      ENSRNOP00000071591.2, ENSRNOT00000091751.3
      Conserved Domains (1) summary
      cd06880
      Location:2 → 116
      PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      75503297..75509271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265163.1 → XP_063121233.1  sorting nexin-22 isoform X2

    2. XM_006243305.5 → XP_006243367.1  sorting nexin-22 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K0V0
      Related
      ENSRNOP00000104441.1, ENSRNOT00000130223.1
      Conserved Domains (1) summary
      cd06880
      Location:2 → 116
      PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22

    3. XM_006243304.5 → XP_006243366.1  sorting nexin-22 isoform X1

      Conserved Domains (1) summary
      cl02563
      Location:31 → 122
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
    Nucleotide Protein Strain
    Heading Accession and Version

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