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    Epsti1 epithelial stromal interaction 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498547, updated on 27-Dec-2024

    Summary

    Official Symbol
    Epsti1provided by RGD
    Official Full Name
    epithelial stromal interaction 1provided by RGD
    Primary source
    RGD:1563207
    See related
    EnsemblRapid:ENSRNOG00000009471 AllianceGenome:RGD:1563207
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563207
    Summary
    Predicted to act upstream of or within several processes, including cellular response to lipopolysaccharide; cellular response to type II interferon; and macrophage differentiation. Orthologous to human EPSTI1 (epithelial stromal interaction 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 214.5), Spleen (RPKM 192.2) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Epsti1 in Genome Data Viewer
    Location:
    15q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (59692712..59791376)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (53283964..53382192)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (60084966..60190360)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene ecto-NOX disulfide-thiol exchanger 1 Neighboring gene uncharacterized LOC120097117 Neighboring gene DnaJ heat shock protein family (Hsp40) member C15 Neighboring gene family with sequence similarity 216, member B Neighboring gene TNF superfamily member 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    epithelial-stromal interaction protein 1
    Names
    epithelial stromal interaction 1 (breast)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044257.1NP_001037722.1  epithelial-stromal interaction protein 1

      See identical proteins and their annotated locations for NP_001037722.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091212
      UniProtKB/Swiss-Prot
      Q5BK43
      UniProtKB/TrEMBL
      A6HTX0
      Related
      ENSRNOP00000012632.4, ENSRNOT00000012632.7
      Conserved Domains (1) summary
      pfam03763
      Location:71164
      Remorin_C; Remorin, C-terminal region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      59692712..59791376
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093594.2XP_038949522.1  epithelial-stromal interaction protein 1 isoform X1