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    Cldn20 claudin 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680178, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cldn20provided by RGD
    Official Full Name
    claudin 20provided by RGD
    Primary source
    RGD:1595446
    See related
    EnsemblRapid:ENSRNOG00000073115 AllianceGenome:RGD:1595446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in Golgi apparatus; cytosol; and tight junction. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN20 (claudin 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cldn20 in Genome Data Viewer
    Location:
    1q11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (46539039..46539698)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (44133769..44134428)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (44443218..44447595)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SR-related CTD-associated factor 8 Neighboring gene TIAM Rac1 associated GEF 2 Neighboring gene transmembrane protein 127, pseudogene 1 Neighboring gene transcription factor B1, mitochondrial Neighboring gene uncharacterized LOC120099111 Neighboring gene NADPH oxidase 3

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in tight junction ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109394.1NP_001102864.1  claudin-20 precursor

      See identical proteins and their annotated locations for NP_001102864.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474052
      UniProtKB/TrEMBL
      A6KIQ7, D3ZT28
      Related
      ENSRNOP00000105337.1, ENSRNOT00000168490.1
      Conserved Domains (1) summary
      cl21598
      Location:5181
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      46539039..46539698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)