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    Asb7 ankyrin repeat and SOCS box-containing 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 365277, updated on 9-Dec-2024

    Summary

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    Symbol
    Asb7provided by RGD
    Full Name
    ankyrin repeat and SOCS box-containing 7provided by RGD
    Primary source
    RGD:1305154
    See related
    EnsemblRapid:ENSRNOG00000013795 AllianceGenome:RGD:1305154
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in intracellular signal transduction and protein ubiquitination. Orthologous to human ASB7 (ankyrin repeat and SOCS box containing 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 54.7), Thymus (RPKM 44.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Asb7 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (129621462..129677788, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (120222835..120267411, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (127545671..127599257, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) 55 Neighboring gene uncharacterized LOC134485131 Neighboring gene lines homolog 1 Neighboring gene ceramide synthase 3 Neighboring gene heat shock cognate 71 kDa protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 7
    Names
    ankyrin repeat and SOCS box-containing protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108915.2 → NP_001102385.1  ankyrin repeat and SOCS box protein 7

      See identical proteins and their annotated locations for NP_001102385.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZQV9, A6JBQ8
      Related
      ENSRNOP00000080514.2, ENSRNOT00000095353.2
      Conserved Domains (4) summary
      PTZ00322
      Location:219 → 272
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PHA02875
      Location:21 → 241
      PHA02875; ankyrin repeat protein; Provisional
      cd03726
      Location:273 → 317
      SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
      sd00045
      Location:81 → 114
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      129621462..129677788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229350.5 → XP_006229412.1  ankyrin repeat and SOCS box protein 7 isoform X1

      See identical proteins and their annotated locations for XP_006229412.1

      UniProtKB/TrEMBL
      A0A8I5ZQV9, A6JBQ8
      Conserved Domains (4) summary
      PTZ00322
      Location:219 → 272
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PHA02875
      Location:21 → 241
      PHA02875; ankyrin repeat protein; Provisional
      cd03726
      Location:273 → 317
      SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
      sd00045
      Location:81 → 114
      ANK; ANK repeat [structural motif]

    2. XM_006229349.5 → XP_006229411.1  ankyrin repeat and SOCS box protein 7 isoform X1

      See identical proteins and their annotated locations for XP_006229411.1

      UniProtKB/TrEMBL
      A0A8I5ZQV9, A6JBQ8
      Conserved Domains (4) summary
      PTZ00322
      Location:219 → 272
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PHA02875
      Location:21 → 241
      PHA02875; ankyrin repeat protein; Provisional
      cd03726
      Location:273 → 317
      SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
      sd00045
      Location:81 → 114
      ANK; ANK repeat [structural motif]

    3. XM_039085011.2 → XP_038940939.1  ankyrin repeat and SOCS box protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZQV9, A6JBQ8
      Conserved Domains (4) summary
      PTZ00322
      Location:219 → 272
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PHA02875
      Location:21 → 241
      PHA02875; ankyrin repeat protein; Provisional
      cd03726
      Location:273 → 317
      SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
      sd00045
      Location:81 → 114
      ANK; ANK repeat [structural motif]

    4. XM_063269228.1 → XP_063125298.1  ankyrin repeat and SOCS box protein 7 isoform X2

      UniProtKB/TrEMBL
      D3ZVT6
      Related
      ENSRNOP00000018436.4, ENSRNOT00000018436.7

    5. XM_063269231.1 → XP_063125301.1  ankyrin repeat and SOCS box protein 7 isoform X3

    RNA

    1. XR_010055191.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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