Krt35 keratin 35 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Krt35provided by RGD
Official Full Name: keratin 35provided by RGD
Primary source: RGD:1305300
See related: EnsemblRapid:ENSRNOG00000013754 AllianceGenome:RGD:1305300
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ka30; Krt1-2
Summary: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Orthologous to human KRT35 (keratin 35). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 7.4) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q31

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (85526571..85529968, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (85026171..85029568, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (88006179..88009576, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in epithelial cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type I cuticular Ha5

Names: keratin 35, type I; keratin complex 1, acidic, gene 2; type I hair keratin KA30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008820.1 → NP_001008820.1 keratin, type I cuticular Ha5

See identical proteins and their annotated locations for NP_001008820.1

Status: PROVISIONAL

Source sequence(s)

BK004042

UniProtKB/TrEMBL

F7F336, Q6IFV6

Related

ENSRNOP00000018566.2, ENSRNOT00000018566.5

Conserved Domains (3) summary

pfam00038
Location:96 → 407

Filament; Intermediate filament protein

pfam16888
Location:305 → 408

DUF5082; Domain of unknown function (DUF5082)

cl00459
Location:192 → 334

MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily