Pcdhb8 protocadherin beta 8 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pcdhb8provided by RGD
Official Full Name: protocadherin beta 8provided by RGD
Primary source: RGD:1309895
See related: EnsemblRapid:ENSRNOG00000089286 AllianceGenome:RGD:1309895
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable calcium ion binding activity and identical protein binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human PCDHB5 (protocadherin beta 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 18p11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (29339476..29341815)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (29065466..29067805)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (30435119..30437458)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protocadherin beta 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014779.1 → NP_001014779.1 protocadherin beta 8 precursor

See identical proteins and their annotated locations for NP_001014779.1

Status: PROVISIONAL

Source sequence(s)

CH473974

UniProtKB/TrEMBL

A6J364, G3V8N7

Related

ENSRNOP00000110738.1, ENSRNOT00000080650.3

Conserved Domains (3) summary

cd11304
Location:247 → 342

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:31 → 112

Cadherin_2; Cadherin-like

pfam16492
Location:686 → 766

Cadherin_C_2; Cadherin cytoplasmic C-terminal