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    Lrriq3 leucine-rich repeats and IQ motif containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrriq3provided by RGD
    Official Full Name
    leucine-rich repeats and IQ motif containing 3provided by RGD
    Primary source
    RGD:1591943
    See related
    EnsemblRapid:ENSRNOG00000009555 AllianceGenome:RGD:1591943
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lrrc44
    Summary
    Orthologous to human LRRIQ3 (leucine rich repeats and IQ motif containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 314.3) and Spleen (RPKM 13.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrriq3 in Genome Data Viewer
    Location:
    2q45
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (246778759..246871284)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (244119975..244214590)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (261403040..261499893)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta, pseudogene 3 Neighboring gene TNNI3 interacting kinase Neighboring gene leucine rich repeat containing 53 Neighboring gene uncharacterized LOC134486009 Neighboring gene fucose-1-phosphate guanylyltransferase Neighboring gene ribosomal protein L32, pseudogene 7 Neighboring gene uncharacterized LOC134485698

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    leucine-rich repeat and IQ domain-containing protein 3
    Names
    leucine rich repeat containing 44
    leucine-rich repeat-containing protein 44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024307.1 → NP_001019478.1  leucine-rich repeat and IQ domain-containing protein 3

      See identical proteins and their annotated locations for NP_001019478.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078994
      UniProtKB/Swiss-Prot
      Q6AYL8
      UniProtKB/TrEMBL
      A6HWR0
      Related
      ENSRNOP00000012841.5, ENSRNOT00000012841.9
      Conserved Domains (3) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam17380
      Location:388 → 586
      DUF5401; Family of unknown function (DUF5401)
      cd21340
      Location:36 → 128
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      246778759..246871284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282410.1 → XP_063138480.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I6B5F4, A6HWR1
      Related
      ENSRNOP00000097180.1, ENSRNOT00000095686.2

    2. XM_039102961.2 → XP_038958889.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZK36, A6HWR2
      Related
      ENSRNOP00000076522.1, ENSRNOT00000109356.2
      Conserved Domains (2) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      cd21340
      Location:36 → 128
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    3. XM_039102959.2 → XP_038958887.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X2

    4. XM_063282409.1 → XP_063138479.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AYL8.1 GenPept UniProtKB/Swiss-Prot:Q6AYL8

    Gene LinkOut

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