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    Rpl3l ribosomal protein L3-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287122, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpl3lprovided by RGD
    Official Full Name
    ribosomal protein L3-likeprovided by RGD
    Primary source
    RGD:1306315
    See related
    EnsemblRapid:ENSRNOG00000014641 AllianceGenome:RGD:1306315
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of myotube differentiation; regulation of striated muscle tissue development; and translation. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Orthologous to human RPL3L (ribosomal protein L3 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 655.9) and Heart (RPKM 287.5) See more
    Orthologs
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    Genomic context

    See Rpl3l in Genome Data Viewer
    Location:
    10q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (14258446..14268989)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13753914..13764458)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14094769..14105312)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, H/ACA box 64 Neighboring gene ribosomal protein S2 Neighboring gene NADH:ubiquinone oxidoreductase subunit B10 Neighboring gene methionine sulfoxide reductase B1 Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 6

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of myotube differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of striated muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribosomal protein uL3-like
    Names
    60S ribosomal protein L3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191589.1NP_001178518.1  ribosomal protein uL3-like

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      D4A9G1
      Related
      ENSRNOP00000019660.5, ENSRNOT00000019660.9
      Conserved Domains (2) summary
      PTZ00103
      Location:1400
      PTZ00103; 60S ribosomal protein L3; Provisional
      cl00324
      Location:7373
      RplC; Ribosomal protein L3 [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      14258446..14268989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)