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    Taf9 TATA-box binding protein associated factor 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 373541, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Taf9provided by RGD
    Official Full Name
    TATA-box binding protein associated factor 9provided by RGD
    Primary source
    RGD:727861
    See related
    EnsemblRapid:ENSRNOG00000039848 AllianceGenome:RGD:727861
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    CINAP; TAFII31; TAFII32
    Summary
    Predicted to enable several functions, including ATPase binding activity; C2H2 zinc finger domain binding activity; and p53 binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity and histone acetyltransferase activity. Involved in positive regulation of transcription by RNA polymerase II and response to L-glutamate. Predicted to be located in nucleoplasm. Predicted to be part of SAGA complex; nucleoplasm; and pre-snoRNP complex. Orthologous to human TAF9 (TATA-box binding protein associated factor 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 1068.7), Thymus (RPKM 309.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Taf9 in Genome Data Viewer
    Location:
    2q12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (33528388..33532395)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (31794316..31798324)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (30664407..30668414)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene bolA-like 1-like Neighboring gene uncharacterized LOC102557393 Neighboring gene MARVEL domain containing 2 Neighboring gene RAD17 checkpoint clamp loader component Neighboring gene adenylate kinase 6 Neighboring gene coiled-coil domain containing 125 Neighboring gene cyclin-dependent kinase 7 Neighboring gene KtI12 chromatin associated, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression differences of regenerating rat liver in a short interval successive partial hepatectomy. Xu CS, et al. World J Gastroenterol, 2004 Sep 15. PMID 15309719, Free PMC Article
    2. Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF. Aoki T, et al. Biochem Biophys Res Commun, 1997 May 8. PMID 9168994
    3. The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32. Fontes JD, et al. Nucleic Acids Res, 1997 Jun 15. PMID 9171108, Free PMC Article
    4. In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. Chen Z, et al. J Biol Chem, 2003 Sep 12. PMID 12837753
    5. Stabilization and activation of p53 by the coactivator protein TAFII31. Buschmann T, et al. J Biol Chem, 2001 Apr 27. PMID 11278372

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC108535

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables C2H2 zinc finger domain binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables C2H2 zinc finger domain binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dephospho-CoA kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables p53 binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables p53 binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in box C/D snoRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in box C/D snoRNP assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in coenzyme A biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in nucleoside monophosphate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of response to cytokine stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of response to cytokine stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription initiation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription initiation by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to L-glutamate IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to interleukin-1 ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of MLL1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of MLL1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SAGA complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of SAGA complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of pre-snoRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of pre-snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription factor TFTC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFTC complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFTC complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 9
    Names
    RNA polymerase II TBP-associated factor subunit G
    TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
    TAF9 RNA polymerase II, TATA box binding protein-associated factor
    transcription initiation factor TFIID 31 kDa subunit
    transcription initiation factor TFIID 32 kDa subunit
    NP_001032387.1
    NP_908937.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037310.1 → NP_001032387.1  transcription initiation factor TFIID subunit 9

      See identical proteins and their annotated locations for NP_001032387.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longer transcript. Both variants 2 and 3 encode the same protein.
      Source sequence(s)
      BC091109, CB724309, CV127122
      UniProtKB/Swiss-Prot
      Q5BKE0, Q6UV34, Q7TP20
      UniProtKB/TrEMBL
      A0A8L2QZB8, A6I598
      Conserved Domains (1) summary
      pfam02291
      Location:9 → 129
      TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

    2. NM_184048.2 → NP_908937.2  transcription initiation factor TFIID subunit 9

      See identical proteins and their annotated locations for NP_908937.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Both variants 2 and 3 encode the same protein.
      Source sequence(s)
      BC091109, CB743840
      UniProtKB/Swiss-Prot
      Q5BKE0, Q6UV34, Q7TP20
      UniProtKB/TrEMBL
      A0A8L2QZB8, A6I598
      Related
      ENSRNOP00000068424.2, ENSRNOT00000076786.4
      Conserved Domains (1) summary
      pfam02291
      Location:9 → 129
      TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      33528388..33532395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BKE0.1 GenPept UniProtKB/Swiss-Prot:Q5BKE0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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