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    Zfp729b zinc finger protein 729b [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680258, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Zfp729bprovided by RGD
    Official Full Name
    zinc finger protein 729bprovided by RGD
    Primary source
    RGD:1594173
    See related
    EnsemblRapid:ENSRNOG00000069921 AllianceGenome:RGD:1594173
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp748l1
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 60.7), Spleen (RPKM 54.7) and 9 other tissues See more
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    Genomic context

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    See Zfp729b in Genome Data Viewer
    Location:
    1p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (36931111..36965484, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (35102732..35137107, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (37977333..38009465, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 728-like Neighboring gene zinc finger protein 748 Neighboring gene sprouty RTK signaling antagonist 3, pseudogene 1 Neighboring gene zinc finger protein 729

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery. Peng H, et al. J Biol Chem, 2009 Dec 18. PMID 19850934, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 729b
    Names
    zinc finger protein 728
    zinc finger protein 728-like
    zinc finger protein 748 like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408775.1 → NP_001395704.1  zinc finger protein 729b isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      Related
      ENSRNOP00000084653.2, ENSRNOT00000105741.2

    2. NM_001408776.1 → NP_001395705.1  zinc finger protein 729b isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      36931111..36965484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099396.1 → XP_038955324.1  zinc finger protein 729b isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1R7
      Conserved Domains (4) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:607 → 1022
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:132 → 200
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:780 → 800
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_063273618.1 → XP_063129688.1  zinc finger protein 729b isoform X2

    3. XM_039099415.2 → XP_038955343.1  zinc finger protein 729b isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1R7
      Conserved Domains (4) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:607 → 1022
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:132 → 200
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:780 → 800
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_063273617.1 → XP_063129687.1  zinc finger protein 729b isoform X2

    5. XM_039099402.2 → XP_038955330.1  zinc finger protein 729b isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1R7
      Conserved Domains (4) summary
      smart00349
      Location:2 → 61
      KRAB; krueppel associated box
      COG5048
      Location:607 → 1022
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:132 → 200
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:780 → 800
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_063273611.1 → XP_063129681.1  zinc finger protein 729b isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1R7
    Nucleotide Protein Strain
    Heading Accession and Version

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