U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    C1qtnf2 C1q and TNF related 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497886, updated on 9-Dec-2024

    Summary

    Official Symbol
    C1qtnf2provided by RGD
    Official Full Name
    C1q and TNF related 2provided by RGD
    Primary source
    RGD:1561041
    See related
    EnsemblRapid:ENSRNOG00000003870 AllianceGenome:RGD:1561041
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Adih; Ctrp2; RGD1561041
    Summary
    Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in regulation of lipid metabolic process. Predicted to act upstream of or within positive regulation of D-glucose import; positive regulation of MAPK cascade; and positive regulation of small molecule metabolic process. Predicted to be located in extracellular space. Predicted to be part of protein-containing complex. Orthologous to human C1QTNF2 (C1q and TNF related 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 117.5), Heart (RPKM 107.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See C1qtnf2 in Genome Data Viewer
    Location:
    10q21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (28443326..28460400)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (27941948..27958926)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (29067102..29084035)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene PTTG1 regulator of sister chromatid separation, securin Neighboring gene SLU7 homolog, splicing factor Neighboring gene uncharacterized LOC108352074 Neighboring gene cyclin J-like Neighboring gene uncharacterized LOC134480674

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in extracellular space  
    part_of protein-containing complex  

    General protein information

    Preferred Names
    complement C1q tumor necrosis factor-related protein 2
    Names
    C1q and tumor necrosis factor related protein 2
    adiponectin h

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191918.1 → NP_001178847.1  complement C1q tumor necrosis factor-related protein 2 precursor

      See identical proteins and their annotated locations for NP_001178847.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A3B0J1M6, A0A8I6AKQ7
      Conserved Domains (2) summary
      pfam01391
      Location:76 → 130
      Collagen; Collagen triple helix repeat (20 copies)
      pfam00386
      Location:160 → 284
      C1q; C1q domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      28443326..28460400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086544.2 → XP_038942472.1  complement C1q tumor necrosis factor-related protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3B0J1M6, D3ZCS2
      Related
      ENSRNOP00000077656.2, ENSRNOT00000097801.2
      Conserved Domains (2) summary
      pfam00386
      Location:151 → 275
      C1q; C1q domain
      pfam01391
      Location:70 → 122
      Collagen; Collagen triple helix repeat (20 copies)
    Loading
    External link. Please review our privacy policy.