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    Cox6b2 cytochrome c oxidase subunit 6B2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 654441, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cox6b2provided by RGD
    Official Full Name
    cytochrome c oxidase subunit 6B2provided by RGD
    Primary source
    RGD:1591896
    See related
    EnsemblRapid:ENSRNOG00000077802 AllianceGenome:RGD:1591896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in oxidative phosphorylation. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrial crista. Orthologous to human COX6B2 (cytochrome c oxidase subunit 6B2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 420.7) and Lung (RPKM 14.6) See more
    Orthologs
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    Genomic context

    See Cox6b2 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (78122871..78124096)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (69094009..69095312)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72661099..72662436)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene interleukin 11 Neighboring gene golgi associated RAB2 interactor family member 5B Neighboring gene lysine methyltransferase 5C Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in mitochondrial crista  
    located_in mitochondrial crista  
    is_active_in mitochondrion  
    located_in mitochondrion PubMed 
    part_of respiratory chain complex IV  

    General protein information

    Preferred Names
    cytochrome c oxidase subunit 6B2
    Names
    COX VIb-2
    cytochrome c oxidase subunit VIb polypeptide 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039085.1NP_001034174.1  cytochrome c oxidase subunit 6B2

      See identical proteins and their annotated locations for NP_001034174.1

      Status: VALIDATED

      Source sequence(s)
      AY152399, CK840972
      UniProtKB/Swiss-Prot
      Q6YFQ1
      UniProtKB/TrEMBL
      A6KNN4
      Related
      ENSRNOP00000107965.1, ENSRNOT00000127328.1
      Conserved Domains (1) summary
      cd00926
      Location:1587
      Cyt_c_Oxidase_VIb; Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      78122871..78124096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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