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    Zfp715 zinc finger protein 715 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100360772, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp715provided by RGD
    Official Full Name
    zinc finger protein 715provided by RGD
    Primary source
    RGD:1624201
    See related
    EnsemblRapid:ENSRNOG00000024056 AllianceGenome:RGD:1624201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dzf17; Zfp17
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF585B (zinc finger protein 585B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 128.7), Thymus (RPKM 123.4) and 9 other tissues See more
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    Genomic context

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    See Zfp715 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (102844466..102884730, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (93706005..93748131, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (98614943..98631142)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 431 like 12 Neighboring gene interferon stimulated exonuclease gene 20 like 1 Neighboring gene sialic acid binding Ig-like lectin 5 Neighboring gene sialic acid binding Ig-like lectin 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Gebelein B, et al. Cancer Lett, 1996 Aug 2. PMID 8697448
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 260; zinc finger protein 665; zinc finger protein 715; zinc finger protein ZFP2
    Names
    zinc finger protein 17
    zinc finger protein 2 homolog
    zinc finger protein 260-like
    zinc finger protein 585B
    zinc finger protein 665-like
    zinc finger protein 708

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432725.1 → NP_001419654.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    2. NM_001432726.1 → NP_001419655.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    3. NM_001432727.1 → NP_001419656.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    4. NM_001432728.1 → NP_001419657.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    5. NM_001432729.1 → NP_001419658.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    6. NM_001432730.1 → NP_001419659.1  zinc finger protein 715 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZZL4

    7. NM_001432731.1 → NP_001419660.1  zinc finger protein 715 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6A558

    8. NM_001432732.1 → NP_001419661.1  zinc finger protein 715 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      102844466..102884730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100894.2 → XP_038956822.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    2. XM_063278100.1 → XP_063134170.1  zinc finger protein ZFP2 isoform X3

    3. XM_063278102.1 → XP_063134172.1  zinc finger protein ZFP2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A558

    4. XM_039100897.2 → XP_038956825.1  zinc finger protein ZFP2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A558
      Conserved Domains (4) summary
      COG5048
      Location:356 → 758
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:388 → 408
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:27 → 66
      KRAB; KRAB box
      pfam13465
      Location:764 → 788
      zf-H2C2_2; Zinc-finger double domain

    5. XM_039100896.2 → XP_038956824.1  zinc finger protein ZFP2 isoform X2

      Conserved Domains (4) summary
      smart00349
      Location:5 → 62
      KRAB; krueppel associated box
      COG5048
      Location:366 → 768
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:398 → 418
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:774 → 798
      zf-H2C2_2; Zinc-finger double domain

    6. XM_017590090.3 → XP_017445579.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    7. XM_017590083.3 → XP_017445572.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    8. XM_017590079.3 → XP_017445568.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    9. XM_017590089.3 → XP_017445578.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    10. XM_017590078.3 → XP_017445567.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    11. XM_017590077.3 → XP_017445566.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    12. XM_039100895.2 → XP_038956823.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    13. XM_017590086.3 → XP_017445575.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    14. XM_017590081.3 → XP_017445570.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    15. XM_017590091.3 → XP_017445580.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4
      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    16. XM_017590084.3 → XP_017445573.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    17. XM_017590080.3 → XP_017445569.1  zinc finger protein 665 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:27 → 84
      KRAB; krueppel associated box
      COG5048
      Location:388 → 790
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:420 → 440
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:796 → 820
      zf-H2C2_2; Zinc-finger double domain

    18. XM_063278053.1 → XP_063134123.1  zinc finger protein 665 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZL4

    19. XM_017590094.3 → XP_017445583.1  zinc finger protein 260 isoform X4

      UniProtKB/TrEMBL
      F1M700
      Related
      ENSRNOP00000100675.1, ENSRNOT00000152576.1
    Nucleotide Protein Strain
    Heading Accession and Version

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