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    Klrg1 killer cell lectin like receptor G1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 58975, updated on 9-Dec-2024

    Summary

    Official Symbol
    Klrg1provided by RGD
    Official Full Name
    killer cell lectin like receptor G1provided by RGD
    Primary source
    RGD:61978
    See related
    EnsemblRapid:ENSRNOG00000014918 AllianceGenome:RGD:61978
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MAFA
    Summary
    Enables carbohydrate binding activity. Predicted to be involved in innate immune response. Predicted to be located in intracellular membrane-bounded organelle. Orthologous to human KLRG1 (killer cell lectin like receptor G1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 29.8), Lung (RPKM 24.0) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Klrg1 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (157127571..157139372, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (155455465..155467301, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (155038936..155051449, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene C3 and PZP-like, alpha-2-macroglobulin domain containing 8 Neighboring gene thymosin beta-10-like Neighboring gene uncharacterized LOC134486841 Neighboring gene mannose-6-phosphate receptor, cation dependent Neighboring gene polyhomeotic homolog 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle  
    located_in membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    killer cell lectin-like receptor subfamily G member 1
    Names
    killer cell lectin-like receptor subfamily G, member 1
    mast cell function-associated antigen

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031649.3NP_113837.1  killer cell lectin-like receptor subfamily G member 1

      See identical proteins and their annotated locations for NP_113837.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/Swiss-Prot
      Q64335
      UniProtKB/TrEMBL
      A0A8L2QB90
      Related
      ENSRNOP00000020094.5, ENSRNOT00000020094.7
      Conserved Domains (1) summary
      cd03593
      Location:75185
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      157127571..157139372 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237313.5XP_006237375.1  killer cell lectin-like receptor subfamily G member 1 isoform X1

      Conserved Domains (1) summary
      cd03593
      Location:40150
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    2. XM_039108299.2XP_038964227.1  killer cell lectin-like receptor subfamily G member 1 isoform X2

      Conserved Domains (1) summary
      cd03593
      Location:36146
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
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