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    Ldlrad3 low density lipoprotein receptor class A domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366138, updated on 9-Dec-2024

    Summary

    Symbol
    Ldlrad3provided by RGD
    Full Name
    low density lipoprotein receptor class A domain containing 3provided by RGD
    Primary source
    RGD:1307846
    See related
    EnsemblRapid:ENSRNOG00000058157 AllianceGenome:RGD:1307846
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307846
    Summary
    Predicted to enable amyloid-beta binding activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within regulation of protein processing. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human LDLRAD3 (low density lipoprotein receptor class A domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 38.0), Kidney (RPKM 36.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ldlrad3 in Genome Data Viewer
    Location:
    3q31-q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (108694528..108936330, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (88239529..88481340, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (91596730..91839054, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene proline rich 5 like Neighboring gene COMM domain containing 9 Neighboring gene uncharacterized LOC134486413 Neighboring gene uncharacterized LOC120101606 Neighboring gene large ribosomal subunit protein eL21 Neighboring gene uncharacterized LOC134486129

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    low-density lipoprotein receptor class A domain-containing protein 3
    Names
    low-density lipoprotein receptor class A domain-containing protein 3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401870.1 → NP_001388799.1  low-density lipoprotein receptor class A domain-containing protein 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      F1LXB2
      Related
      ENSRNOP00000069591.1, ENSRNOT00000083703.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      108694528..108936330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592181.3 → XP_017447670.1  low-density lipoprotein receptor class A domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A6HNN4
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