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    Elp5 elongator acetyltransferase complex subunit 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287446, updated on 9-Dec-2024

    Summary

    Official Symbol
    Elp5provided by RGD
    Official Full Name
    elongator acetyltransferase complex subunit 5provided by RGD
    Primary source
    RGD:1303303
    See related
    EnsemblRapid:ENSRNOG00000027628 AllianceGenome:RGD:1303303
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    DERP6; Rai12
    Summary
    Predicted to contribute to tRNA binding activity. Predicted to be involved in positive regulation of cell migration and tRNA modification. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytosol and nucleus. Orthologous to human ELP5 (elongator acetyltransferase complex subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 79.4), Adrenal (RPKM 78.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Elp5 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55191223..55202949, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54692526..54704255, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56578980..56590706, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene cofilin-1-like Neighboring gene claudin 7 Neighboring gene CTD nuclear envelope phosphatase 1 Neighboring gene GABA type A receptor-associated protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to tRNA binding  
    Process Evidence Code Pubs
    involved_in positive regulation of cell migration  
    involved_in positive regulation of cell migration  
    involved_in positive regulation of cell migration  
    involved_in tRNA modification  
    involved_in tRNA wobble uridine modification  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    located_in cytosol  
    part_of elongator holoenzyme complex  
    part_of elongator holoenzyme complex  
    part_of elongator holoenzyme complex  
    part_of elongator holoenzyme complex  
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    elongator complex protein 5
    Names
    S-phase 2 protein
    dermal papilla derived protein 6
    dermal papilla-derived protein 6 homolog
    retinoic acid induced 12
    retinoic acid-induced protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001718.1NP_001001718.1  elongator complex protein 5

      See identical proteins and their annotated locations for NP_001001718.1

      Status: PROVISIONAL

      Source sequence(s)
      AY623900
      UniProtKB/Swiss-Prot
      Q6IUP3
      UniProtKB/TrEMBL
      A6HFY9
      Conserved Domains (1) summary
      cd19496
      Location:30192
      Elp5; Elongator subcomplex subunit Elp5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55191223..55202949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597092.1XP_017452581.1  elongator complex protein 5 isoform X1

      UniProtKB/TrEMBL
      B0BMU7
      Related
      ENSRNOP00000035345.5, ENSRNOT00000032481.7
      Conserved Domains (1) summary
      pfam10483
      Location:19302
      Elong_Iki1; Elongator subunit Iki1
    2. XM_063268644.1XP_063124714.1  elongator complex protein 5 isoform X3

      UniProtKB/TrEMBL
      A6HFZ1
    3. XM_039085463.2XP_038941391.1  elongator complex protein 5 isoform X2

      Conserved Domains (1) summary
      cd19496
      Location:30160
      Elp5; Elongator subcomplex subunit Elp5

    RNA

    1. XR_005489736.2 RNA Sequence

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