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    Mnd1 meiotic nuclear divisions 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295160, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mnd1provided by RGD
    Official Full Name
    meiotic nuclear divisions 1provided by RGD
    Primary source
    RGD:1309007
    See related
    EnsemblRapid:ENSRNOG00000024733 AllianceGenome:RGD:1309007
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309007
    Summary
    Predicted to enable double-stranded DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and reciprocal meiotic recombination. Predicted to be located in nucleus. Orthologous to human MND1 (meiotic nuclear divisions 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 17.1), Testes (RPKM 15.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mnd1 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (171731523..171794124, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (169433523..169496081, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (183073029..183140768, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485933 Neighboring gene peflin pseudogene Neighboring gene tripartite motif-containing 2 Neighboring gene uncharacterized LOC102550635 Neighboring gene uncharacterized LOC134485931

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in homologous chromosome pairing at meiosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in reciprocal meiotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in reciprocal meiotic recombination ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    meiotic nuclear division protein 1 homolog
    Names
    meiotic nuclear divisions 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398663.1 → NP_001385592.1  meiotic nuclear division protein 1 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      F1LWN6
      Related
      ENSRNOP00000034074.5, ENSRNOT00000031179.7
      Conserved Domains (1) summary
      COG5124
      Location:5 → 204
      COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      171731523..171794124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281594.1 → XP_063137664.1  meiotic nuclear division protein 1 homolog isoform X3

    2. XM_063281592.1 → XP_063137662.1  meiotic nuclear division protein 1 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZQ57, A6J5W1

    3. XM_063281593.1 → XP_063137663.1  meiotic nuclear division protein 1 homolog isoform X2

    4. XM_063281595.1 → XP_063137665.1  meiotic nuclear division protein 1 homolog isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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