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    Cldn22 claudin 22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306454, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cldn22provided by RGD
    Official Full Name
    claudin 22provided by RGD
    Primary source
    RGD:1305271
    See related
    AllianceGenome:RGD:1305271
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN22 (claudin 22). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Cldn22 in Genome Data Viewer
    Location:
    16q11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (51155058..51156084, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (44422344..44423370, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (47534349..47535358, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551022 Neighboring gene WW and C2 domain containing 2 Neighboring gene uncharacterized LOC134482501 Neighboring gene uncharacterized LOC134482379 Neighboring gene claudin 24 Neighboring gene proteasome subunit alpha type-5-like

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly  
    involved_in cell adhesion  
    Component Evidence Code Pubs
    is_active_in bicellular tight junction  
    is_active_in plasma membrane  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110143.2 → NP_001103613.1  claudin-22

      See identical proteins and their annotated locations for NP_001103613.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A6JPK2, D3ZEF2
      Conserved Domains (1) summary
      cl21598
      Location:49 → 183
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      51155058..51156084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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