Abca13 ATP binding cassette subfamily A member 13 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abca13provided by RGD
Official Full Name: ATP binding cassette subfamily A member 13provided by RGD
Primary source: RGD:1305895
See related: EnsemblRapid:ENSRNOG00000025645 AllianceGenome:RGD:1305895
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to be involved in ceramide transport; positive regulation of cholesterol transport; and positive regulation of synaptic vesicle endocytosis. Predicted to be located in intracellular vesicle. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Orthologous to human ABCA13 (ATP binding cassette subfamily A member 13). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 5.3), Thymus (RPKM 1.3) and 5 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14q21

Exon count:: 62

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (88087146..88589868)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (83873397..84376138)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (89384512..89876748)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Abca13 (e-PCR), detects polymorphism
- UniSTS:546610

AI843389 (e-PCR)
- UniSTS:164531

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables lipid transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in ceramide transport	ISO Inferred from Sequence Orthology more info
involved_in lipid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cholesterol transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic vesicle endocytosis	ISO Inferred from Sequence Orthology more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info
located_in intracellular vesicle	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-binding cassette sub-family A member 13

Names: ATP-binding cassette, sub-family A (ABC1), member 13; ATP-binding cassette, subfamily A (ABC1), member 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086032.1 Reference GRCr8

Range

88087146..88589868

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063273790.1 → XP_063129860.1 ATP-binding cassette sub-family A member 13

UniProtKB/TrEMBL

A0A8I6ABQ0

Related

ENSRNOP00000095482.2, ENSRNOT00000107084.2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001106020.2: Suppressed sequence

Description

NM_001106020.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.