Hist1h2bg histone cluster 1, H2bg [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Hist1h2bgprovided by RGD
Official Full Name: histone cluster 1, H2bgprovided by RGD
Primary source: RGD:621439
See related: EnsemblRapid:ENSRNOG00000070362 AllianceGenome:RGD:621439
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: H2b; Hist1h2bl
Summary: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in defense response to bacterium. Predicted to be located in nucleoplasm. Predicted to be part of nucleosome. Orthologous to human H2BC9 (H2B clustered histone 9). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 17p11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (41999269..42000237)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (41571234..41572202)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (43817316..43817717)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Monoubiquitination of histone H2B is a crucial regulator of the transcriptome during memory formation.
Title: Monoubiquitination of histone H2B is a crucial regulator of the transcriptome during memory formation.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Hist1h2bc (e-PCR), detects polymorphism
- UniSTS:259084

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in defense response to bacterium	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	TAS Traceable Author Statement more info
part_of nucleosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: histone H2B type 1

Names: histone 1, H2bl; histone 2b; histone cluster 1, H2bl

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.