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    Yae1 YAE1 maturation factor of ABCE1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306994, updated on 9-Dec-2024

    Summary

    Official Symbol
    Yae1provided by RGD
    Official Full Name
    YAE1 maturation factor of ABCE1provided by RGD
    Primary source
    RGD:1306613
    See related
    EnsemblRapid:ENSRNOG00000013438 AllianceGenome:RGD:1306613
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Yae1d1; RGD1306613
    Summary
    Predicted to be involved in protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in cytoplasm and nucleus. Orthologous to human YAE1 (YAE1 maturation factor of ABCE1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 171.7), Kidney (RPKM 121.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Yae1 in Genome Data Viewer
    Location:
    17q11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (51722582..51729098)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (47027033..47033549)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (49610548..49617065)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene TGFB-induced factor homeobox 2, pseudogene 1 Neighboring gene ZW10 interactor pseudogene Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene ADP-ribosylation factor 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein maturation by [4Fe-4S] cluster transfer ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein YAE1 homolog
    Names
    YAE1, ABCE1 maturation factor
    Yae1 domain containing 1
    yae1 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107356.2NP_001100826.1  protein YAE1 homolog

      See identical proteins and their annotated locations for NP_001100826.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6K997, A6K998, D4AEK7
      Related
      ENSRNOP00000017955.5, ENSRNOT00000017955.7
      Conserved Domains (1) summary
      pfam09811
      Location:4482
      Yae1_N; Essential protein Yae1, N terminal

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      51722582..51729098
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)