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    Hist2h3c2 histone cluster 2 H3 family member C2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310678, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hist2h3c2provided by RGD
    Official Full Name
    histone cluster 2 H3 family member C2provided by RGD
    Primary source
    RGD:1306445
    See related
    EnsemblRapid:ENSRNOG00000070591 AllianceGenome:RGD:1306445
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in nucleosome assembly. Predicted to be located in nucleoplasm. Predicted to be part of nucleosome. Orthologous to several human genes including H3C14 (H3 clustered histone 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 4783.0), Spleen (RPKM 3451.8) and 5 other tissues See more
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    Genomic context

    See Hist2h3c2 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (186526162..186526587)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (183837296..183837721)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (198390024..198418075)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene H2A clustered histone 18 Neighboring gene H4 clustered histone 14 Neighboring gene H2B clustered histone 18 Neighboring gene uncharacterized LOC134485653 Neighboring gene Fc gamma receptor 1A

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone cluster 2 H3 family member C2
    Names
    histone 2, H3c2
    histone cluster 2 H3C family member 2
    histone cluster 2, H3c2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107698.2NP_001101168.1  histone cluster 2 H3 family member C2

      See identical proteins and their annotated locations for NP_001101168.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6KLN8, D3ZJ08
      Related
      ENSRNOP00000109384.1, ENSRNOT00000123128.1
      Conserved Domains (1) summary
      PTZ00018
      Location:1136
      PTZ00018; histone H3; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      186526162..186526587
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)