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    Mymk myomaker, myoblast fusion factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296601, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mymkprovided by RGD
    Official Full Name
    myomaker, myoblast fusion factorprovided by RGD
    Primary source
    RGD:1306074
    See related
    EnsemblRapid:ENSRNOG00000006142 AllianceGenome:RGD:1306074
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem8c; RGD1306074
    Summary
    Predicted to be involved in myoblast fusion; plasma membrane fusion; and positive regulation of skeletal muscle hypertrophy. Predicted to act upstream of or within myoblast fusion involved in skeletal muscle regeneration. Predicted to be located in Golgi membrane and plasma membrane. Human ortholog(s) of this gene implicated in Carey-Fineman-Ziter syndrome. Orthologous to human MYMK (myomaker, myoblast fusion factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 4.0), Heart (RPKM 3.6) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Mymk in Genome Data Viewer
    Location:
    3p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30786443..30795374, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10388363..10397294, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5608243..5617689, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 13 Neighboring gene uncharacterized LOC102548484 Neighboring gene calcium channel flower domain containing 1 Neighboring gene solute carrier family 2 member 6 Neighboring gene ADAMTS-like 2 Neighboring gene family with sequence similarity 163, member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein myomaker
    Names
    transmembrane protein 8C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399315.1NP_001386244.1  protein myomaker

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Related
      ENSRNOP00000008327.3, ENSRNOT00000008327.5
      Conserved Domains (1) summary
      pfam12036
      Location:5185
      DUF3522; Protein of unknown function (DUF3522)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      30786443..30795374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001134517.1: Suppressed sequence

      Description
      NM_001134517.1: This RefSeq was removed because it contains the wrong CDS.