Tas2r108 taste receptor, type 2, member 108 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tas2r108provided by RGD
Official Full Name: taste receptor, type 2, member 108provided by RGD
Primary source: RGD:1561194
See related: EnsemblRapid:ENSRNOG00000012195 AllianceGenome:RGD:1561194
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: T2R16; Tas2r4
Summary: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within respiratory gaseous exchange by respiratory system. Predicted to be located in ciliary membrane. Predicted to be active in membrane. Orthologous to human TAS2R4 (taste 2 receptor member 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 4q23

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (70254367..70255281)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (69287667..69288581)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (68656928..68657842)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bitter taste receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within respiratory gaseous exchange by respiratory system	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in ciliary membrane	IEA Inferred from Electronic Annotation more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: taste receptor type 2 member 4

Names: T2R20; T2R4; bitter taste receptor T2R16; taste receptor type 2 member 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024686.1 → NP_001019857.1 taste receptor type 2 member 4

See identical proteins and their annotated locations for NP_001019857.1

Status: PROVISIONAL

Source sequence(s)

AY916510

UniProtKB/Swiss-Prot

Q67ET0

UniProtKB/TrEMBL

A6IEX8

Related

ENSRNOP00000016232.2, ENSRNOT00000016232.4

Conserved Domains (1) summary

cd15013
Location:7 → 281

7tm_TAS2R4; mammalian taste receptor 2, subtype 4, member of the seven-transmembrane G protein-coupled receptor superfamily