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    Tmed3 transmembrane p24 trafficking protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300888, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmed3provided by RGD
    Official Full Name
    transmembrane p24 trafficking protein 3provided by RGD
    Primary source
    RGD:1303327
    See related
    EnsemblRapid:ENSRNOG00000013889 AllianceGenome:RGD:1303327
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in Golgi apparatus. Part of COPI vesicle coat. Orthologous to human TMED3 (transmembrane p24 trafficking protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 166.5), Spleen (RPKM 154.0) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmed3 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (99121361..99129653, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (90241516..90249429, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (97075194..97083107, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351761 Neighboring gene membrane integral NOTCH2 associated receptor 1 Neighboring gene ankyrin repeat domain 34C Neighboring gene microRNA 184

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC94283

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of COPI vesicle coat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane emp24 domain-containing protein 3
    Names
    integral type I protein
    p24 family protein gamma-4
    p24gamma4
    transmembrane emp24 domain containing 3
    transmembrane emp24 protein transport domain containing 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004249.1NP_001004249.1  transmembrane emp24 domain-containing protein 3 precursor

      See identical proteins and their annotated locations for NP_001004249.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079220
      UniProtKB/Swiss-Prot
      Q6AY25
      UniProtKB/TrEMBL
      A0A8L2QAC1, A6I205
      Related
      ENSRNOP00000018603.6, ENSRNOT00000018603.7
      Conserved Domains (1) summary
      pfam01105
      Location:32209
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      99121361..99129653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265199.1XP_063121269.1  transmembrane emp24 domain-containing protein 3 isoform X1