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    Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501164, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cdk5r2provided by RGD
    Official Full Name
    cyclin-dependent kinase 5 regulatory subunit 2provided by RGD
    Primary source
    RGD:1562530
    See related
    AllianceGenome:RGD:1562530
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562530
    Summary
    Predicted to enable actin binding activity; cyclin-dependent protein serine/threonine kinase activator activity; and protein kinase binding activity. Predicted to be involved in axon guidance and brain development. Predicted to act upstream of or within nervous system development; positive regulation of calcium ion-dependent exocytosis; and positive regulation of protein kinase activity. Located in cytoplasm; growth cone; and membrane. Orthologous to human CDK5R2 (cyclin dependent kinase 5 regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cdk5r2 in Genome Data Viewer
    Location:
    9q33
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (83864922..83866390)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (76416251..76417719)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (82120059..82121527)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene Wnt family member 10A Neighboring gene PCNA-associated factor-like Neighboring gene FEV transcription factor, ETS family member Neighboring gene crystallin, beta A2 Neighboring gene uncharacterized LOC134480387 Neighboring gene microRNA 375

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in cytoplasm PubMed 
    located_in cytoplasm  
    is_active_in growth cone  
    located_in growth cone PubMed 
    located_in membrane PubMed 
    located_in neuron projection PubMed 
    located_in plasma membrane  
    is_active_in presynapse  
    part_of protein kinase 5 complex  

    General protein information

    Preferred Names
    cyclin-dependent kinase 5 activator 2
    Names
    cyclin-dependent kinase 5, regulatory subunit 2 (p39)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109309.1NP_001102779.1  cyclin-dependent kinase 5 activator 2

      See identical proteins and their annotated locations for NP_001102779.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474004
      UniProtKB/TrEMBL
      A6JVW4, F1M491
      Conserved Domains (1) summary
      pfam03261
      Location:174329
      CDK5_activator; Cyclin-dependent kinase 5 activator protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      83864922..83866390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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