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    PSG10P pregnancy specific beta-1-glycoprotein 10, pseudogene [ Homo sapiens (human) ]

    Gene ID: 653492, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PSG10Pprovided by HGNC
    Official Full Name
    pregnancy specific beta-1-glycoprotein 10, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:9515
    See related
    Ensembl:ENSG00000291235 MIM:176399; AllianceGenome:HGNC:9515
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PSG10; PSG12
    Summary
    The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
    Expression
    Restricted expression toward placenta (RPKM 7.0) See more
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    Genomic context

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    See PSG10P in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (42836997..42855718, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (45655941..45674669, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (43341149..43359870, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule pseudogene 6 Neighboring gene PSG8 antisense RNA 1 Neighboring gene pregnancy specific beta-1-glycoprotein 1 Neighboring gene pregnancy specific beta-1-glycoprotein 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Pregnancy-Specific Beta-1-Glycoprotein: The Player of the Game in predicting adverse outcomes in pregnancy. Toprak K, et al. JBRA Assist Reprod, 2023 Jun 22. PMID 36749818, Free PMC Article
    2. Characterization of two allelic variants of a human pregnancy-specific glycoprotein gene. Lei KJ, et al. J Biol Chem, 1993 Aug 15. PMID 8349632
    3. A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene. Oikawa S, et al. Biochem Biophys Res Commun, 1989 Sep 15. PMID 2789512
    4. Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis. Wang N, et al. J Cell Mol Med, 2019 Feb. PMID 30370628, Free PMC Article
    5. cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver. Zimmermann W, et al. Biochem Biophys Res Commun, 1989 Sep 29. PMID 2783133

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pregnancy-Specific Beta-1-Glycoprotein: The Player of the Game in predicting adverse outcomes in pregnancy.
      Title: Pregnancy-Specific Beta-1-Glycoprotein: The Player of the Game in predicting adverse outcomes in pregnancy.
    2. A regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway may contribute to preeclampsia pathogenesis during pregnancy.
      Title: Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • pregnancy specific beta-1-glycoprotein 1 pseudogene
    • pregnancy specific beta-1-glycoprotein 12
    • pregnancy specific beta-1-glycoprotein 120
    • pregnancy-specific beta-1 glycoprotein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026824.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AC004603, AK309876
      Related
      ENST00000730696.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      42836997..42855718 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      45655941..45674669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_176809.2: Suppressed sequence

      Description
      NM_176809.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Chemical Information
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    Research Materials