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    Rad23b RAD23 homolog B, nucleotide excision repair protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298012, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rad23bprovided by RGD
    Official Full Name
    RAD23 homolog B, nucleotide excision repair proteinprovided by RGD
    Primary source
    RGD:1562958
    See related
    EnsemblRapid:ENSRNOG00000016137 AllianceGenome:RGD:1562958
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable several functions, including DNA damage sensor activity; proteasome binding activity; and ubiquitin binding activity. Involved in embryonic organ development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of XPC complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human RAD23B (RAD23 homolog B, nucleotide excision repair protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 531.1), Muscle (RPKM 497.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rad23b in Genome Data Viewer
    Location:
    5q24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (74885518..74923621)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (70090232..70128340)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (72103704..72141701)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S18-like Neighboring gene transfer RNA leucine (anticodon AAG) 10 Neighboring gene uncharacterized LOC134478978 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene KLF transcription factor 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Clone Names

    • MGC112630

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of XPC complex  
    part_of XPC complex  
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    is_active_in nucleoplasm  
    located_in nucleoplasm  
    located_in nucleus  
    located_in nucleus  
    part_of proteasome complex  

    General protein information

    Preferred Names
    UV excision repair protein RAD23 homolog B
    Names
    RAD23b homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025275.1NP_001020446.1  UV excision repair protein RAD23 homolog B

      See identical proteins and their annotated locations for NP_001020446.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098674
      UniProtKB/Swiss-Prot
      Q0D2G8, Q4KMA2, Q5CZZ8, Q6IRD5
      UniProtKB/TrEMBL
      A0A8I6AUT2, A6KDQ3
      Related
      ENSRNOP00000021629.4, ENSRNOT00000021629.8
      Conserved Domains (6) summary
      cd01805
      Location:178
      RAD23_N; Ubiquitin-like domain of RAD23
      cd14377
      Location:189228
      UBA1_Rad23; UBA1 domain of Rad23 proteins found in metazoa
      cd14428
      Location:371415
      UBA2_HR23B; UBA2 domain of UV excision repair protein RAD23 homolog B (HR23B) found in vertebrates
      TIGR00601
      Location:1413
      rad23; UV excision repair protein Rad23
      pfam09280
      Location:276331
      XPC-binding; XPC-binding domain
      pfam12238
      Location:125186
      MSA-2c; Merozoite surface antigen 2c

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      74885518..74923621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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