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    Slc35a5 solute carrier family 35, member A5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498081, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc35a5provided by RGD
    Official Full Name
    solute carrier family 35, member A5provided by RGD
    Primary source
    RGD:1564361
    See related
    EnsemblRapid:ENSRNOG00000002069 AllianceGenome:RGD:1564361
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564361
    Summary
    Predicted to enable pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in Golgi membrane. Orthologous to human SLC35A5 (solute carrier family 35 member A5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 102.9), Thymus (RPKM 75.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc35a5 in Genome Data Viewer
    Location:
    11q21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (69159435..69180503)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (55653376..55674476)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (60613865..60634849)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene B and T lymphocyte associated Neighboring gene autophagy related 3 Neighboring gene coiled-coil domain containing 80 Neighboring gene uncharacterized LOC102551825

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyrimidine nucleotide-sugar transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    UDP-sugar transporter protein SLC35A5
    Names
    probable UDP-sugar transporter protein SLC35A5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191927.1 → NP_001178856.1  UDP-sugar transporter protein SLC35A5

      See identical proteins and their annotated locations for NP_001178856.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6IQZ4, D4A7S3
      Related
      ENSRNOP00000002853.3, ENSRNOT00000002853.7
      Conserved Domains (2) summary
      pfam04142
      Location:37 → 388
      Nuc_sug_transp; Nucleotide-sugar transporter
      cl23754
      Location:228 → 387
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      69159435..69180503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598044.3 → XP_017453533.1  UDP-sugar transporter protein SLC35A5 isoform X3

    2. XM_039088576.2 → XP_038944504.1  UDP-sugar transporter protein SLC35A5 isoform X4

      Conserved Domains (1) summary
      pfam04142
      Location:35 → 314
      Nuc_sug_transp; Nucleotide-sugar transporter

    3. XM_006248343.5 → XP_006248405.1  UDP-sugar transporter protein SLC35A5 isoform X2

      Conserved Domains (2) summary
      pfam04142
      Location:53 → 403
      Nuc_sug_transp; Nucleotide-sugar transporter
      cl23754
      Location:243 → 402
      EamA; EamA-like transporter family

    4. XM_006248342.5 → XP_006248404.1  UDP-sugar transporter protein SLC35A5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AIR5
      Related
      ENSRNOP00000093430.1, ENSRNOT00000098607.2
      Conserved Domains (2) summary
      pfam04142
      Location:53 → 404
      Nuc_sug_transp; Nucleotide-sugar transporter
      cl23754
      Location:244 → 403
      EamA; EamA-like transporter family

    5. XM_063270704.1 → XP_063126774.1  UDP-sugar transporter protein SLC35A5 isoform X5

    6. XM_063270705.1 → XP_063126775.1  UDP-sugar transporter protein SLC35A5 isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

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