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    Zfp513 zinc finger protein 513 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313913, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp513provided by RGD
    Official Full Name
    zinc finger protein 513provided by RGD
    Primary source
    RGD:1310456
    See related
    EnsemblRapid:ENSRNOG00000005298 AllianceGenome:RGD:1310456
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf513
    Summary
    Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and retina development in camera-type eye. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 58. Orthologous to human ZNF513 (zinc finger protein 513). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 49.5), Thymus (RPKM 48.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp513 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (30894153..30897414)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25174181..25177442)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (26537707..26541051)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding protein 1 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1G Neighboring gene sorting nexin 17 Neighboring gene eukaryotic translation initiation factor 2B subunit delta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mutation in ZNF513, a putative regulator of photoreceptor development, causes autosomal-recessive retinitis pigmentosa. Li L, et al. Am J Hum Genet, 2010 Sep 10. PMID 20797688, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105911

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retina development in camera-type eye ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retina development in camera-type eye ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 513

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012110.2 → NP_001012110.1  zinc finger protein 513

      See identical proteins and their annotated locations for NP_001012110.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/Swiss-Prot
      Q5FWU5
      UniProtKB/TrEMBL
      A0A8I6A7V7
      Related
      ENSRNOP00000040002.3, ENSRNOT00000050102.5
      Conserved Domains (3) summary
      COG5048
      Location:414 → 487
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:152 → 172
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:402 → 425
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      30894153..30897414
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FWU5.1 GenPept UniProtKB/Swiss-Prot:Q5FWU5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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