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    Ints6l integrator complex subunit 6 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681665, updated on 27-Dec-2024

    Summary

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    Symbol
    Ints6lprovided by RGD
    Full Name
    integrator complex subunit 6 likeprovided by RGD
    Primary source
    RGD:1592872
    See related
    EnsemblRapid:ENSRNOG00000046662 AllianceGenome:RGD:1592872
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ddx26b
    Summary
    Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Orthologous to human INTS6L (integrator complex subunit 6 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 184.0), Lung (RPKM 88.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ints6l in Genome Data Viewer
    Location:
    Xq36
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (139295490..139363090)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (134258117..134325706)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (158835334..158887055)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134484173 Neighboring gene high-mobility group box 4 like 9 Neighboring gene cancer/testis antigen family 45 member A9 Neighboring gene membrane magnesium transporter 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    integrator complex subunit 6 like; integrator complex subunit 6-like
    Names
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
    cancer/testis antigen family 45 member A5-like
    protein DDX26B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433132.1 → NP_001420061.1  integrator complex subunit 6 like isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I6A4P6, M0RC48

    2. NM_001433133.1 → NP_001420062.1  integrator complex subunit 6 like isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A0G2K0J8, A0A8I6A4P6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      139295490..139363090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100551.2 → XP_038956479.1  integrator complex subunit 6-like isoform X2

      Related
      ENSRNOP00000085913.2, ENSRNOT00000099212.2
      Conserved Domains (2) summary
      pfam13519
      Location:4 → 103
      VWA_2; von Willebrand factor type A domain
      pfam15300
      Location:777 → 838
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    2. XM_039100549.2 → XP_038956477.1  integrator complex subunit 6-like isoform X1

      Related
      ENSRNOP00000067157.3, ENSRNOT00000071888.4
      Conserved Domains (2) summary
      pfam13519
      Location:4 → 103
      VWA_2; von Willebrand factor type A domain
      pfam15300
      Location:814 → 875
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    3. XM_039100552.1 → XP_038956480.1  integrator complex subunit 6-like isoform X3

      UniProtKB/TrEMBL
      A0A8I6A4P6
      Conserved Domains (1) summary
      pfam15300
      Location:741 → 802
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    4. XM_063280545.1 → XP_063136615.1  integrator complex subunit 6-like isoform X4

      UniProtKB/TrEMBL
      A6KSN3

    5. XM_039100554.2 → XP_038956482.1  integrator complex subunit 6-like isoform X5

      Conserved Domains (1) summary
      pfam15300
      Location:429 → 490
      INT_SG_DDX_CT_C; INTS6/SAGE1/DDX26B/CT45 C-terminus

    RNA

    1. XR_005498516.2 RNA Sequence

    2. XR_005498518.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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