Micos13 mitochondrial contact site and cristae organizing system subunit 13 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Micos13provided by RGD
Official Full Name: mitochondrial contact site and cristae organizing system subunit 13provided by RGD
Primary source: RGD:1588578
See related: EnsemblRapid:ENSRNOG00000046002 AllianceGenome:RGD:1588578
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in cristae formation. Predicted to be located in mitochondrial inner membrane and nucleoplasm. Predicted to be part of MICOS complex. Predicted to be active in mitochondrial crista junction. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 37. Orthologous to human MICOS13 (mitochondrial contact site and cristae organizing system subunit 13). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 445.8), Kidney (RPKM 326.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (1526978..1528996, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (1439841..1441782, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (10446567..10449566)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cristae formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in cristae formation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of MICOS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of MICOS complex	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrial crista junction	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial crista junction	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: MICOS complex subunit MIC13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001399202.1 → NP_001386131.1 MICOS complex subunit MIC13 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

UniProtKB/TrEMBL

M0R719

Related

ENSRNOP00000065236.3, ENSRNOT00000075344.3

Conserved Domains (1) summary

pfam15884
Location:25 → 106

QIL1; Protein QIL1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086027.1 Reference GRCr8

Range

1526978..1528996 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063266826.1 → XP_063122896.1 MICOS complex subunit MIC13 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001134533.1: Suppressed sequence

Description

NM_001134533.1: This RefSeq was removed because currently there is support for the transcript but not for the protein.