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    Ints7 integrator complex subunit 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289382, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ints7provided by RGD
    Official Full Name
    integrator complex subunit 7provided by RGD
    Primary source
    RGD:1308014
    See related
    EnsemblRapid:ENSRNOG00000004263 AllianceGenome:RGD:1308014
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308014
    Summary
    Predicted to be involved in DNA damage checkpoint signaling; cellular response to ionizing radiation; and snRNA 3'-end processing. Predicted to be located in chromosome; cytoplasm; and nuclear body. Predicted to be part of integrator complex. Orthologous to human INTS7 (integrator complex subunit 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 207.7), Spleen (RPKM 126.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ints7 in Genome Data Viewer
    Location:
    13q27
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (105686208..105739609)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (103155123..103207953)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (110257571..110310413)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene stratifin, pseudogene 1 Neighboring gene denticleless E3 ubiquitin protein ligase homolog Neighboring gene ribosomal protein L12, pseudogene 10 Neighboring gene ribosomal protein S18, pseudogene 10 Neighboring gene ribosomal protein L37 like 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to ionizing radiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in snRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of integrator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integrator complex subunit 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191675.1NP_001178604.1  integrator complex subunit 7

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A6JH00
      Related
      ENSRNOP00000005715.7, ENSRNOT00000005715.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      105686208..105739609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063272191.1XP_063128261.1  integrator complex subunit 7 isoform X1

      UniProtKB/TrEMBL
      A6JH00