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    Rpp38 ribonuclease P/MRP subunit p38 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291317, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpp38provided by RGD
    Official Full Name
    ribonuclease P/MRP subunit p38provided by RGD
    Primary source
    RGD:1307474
    See related
    EnsemblRapid:ENSRNOG00000063181 AllianceGenome:RGD:1307474
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex. Predicted to be active in fibrillar center. Orthologous to human RPP38 (ribonuclease P/MRP subunit p38). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 40.4), Testes (RPKM 36.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpp38 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79823237..79826908)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (74914066..74917742)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (78915450..78919144)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482748 Neighboring gene oleoyl-ACP hydrolase Neighboring gene acyl-CoA binding domain containing 7 Neighboring gene N-myristoyltransferase 2 Neighboring gene U4 spliceosomal RNA Neighboring gene family with sequence similarity 171, member A1 Neighboring gene uncharacterized LOC134482749 Neighboring gene uncharacterized LOC134482750

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC124666

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ribonuclease P RNA binding  
    enables ribonuclease P RNA binding  
    contributes_to ribonuclease P activity  
    contributes_to ribonuclease P activity  
    Process Evidence Code Pubs
    involved_in biological_process  
    involved_in tRNA 5'-leader removal  
    involved_in tRNA 5'-leader removal  
    Component Evidence Code Pubs
    is_active_in fibrillar center  
    located_in fibrillar center  
    part_of multimeric ribonuclease P complex  
    part_of multimeric ribonuclease P complex  
    part_of nucleolar ribonuclease P complex  
    located_in nucleolus  
    part_of ribonuclease MRP complex  

    General protein information

    Preferred Names
    ribonuclease P protein subunit p38
    Names
    ribonuclease P/MRP 38 subunit
    ribonuclease P/MRP 38kDa subunit
    NP_001028235.1
    XP_006254330.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033063.1NP_001028235.1  ribonuclease P protein subunit p38

      See identical proteins and their annotated locations for NP_001028235.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100623
      UniProtKB/TrEMBL
      A0A8I5YBF8, A6JM24, Q497C2
      Related
      ENSRNOP00000111340.1, ENSRNOT00000133712.1
      Conserved Domains (1) summary
      pfam01248
      Location:100174
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      79823237..79826908
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006254268.5XP_006254330.1  ribonuclease P protein subunit p38 isoform X1

      See identical proteins and their annotated locations for XP_006254330.1

      UniProtKB/TrEMBL
      A0A8I5YBF8, A6JM24, Q497C2
      Conserved Domains (1) summary
      pfam01248
      Location:100174
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
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