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    Dnali1 dynein, axonemal, light intermediate chain 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298524, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dnali1provided by RGD
    Official Full Name
    dynein, axonemal, light intermediate chain 1provided by RGD
    Primary source
    RGD:1309260
    See related
    EnsemblRapid:ENSRNOG00000024957 AllianceGenome:RGD:1309260
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable dynein heavy chain binding activity. Predicted to be involved in sperm flagellum assembly. Predicted to be located in dynein axonemal particle; filopodium; and sperm flagellum. Predicted to be part of dynein complex. Predicted to be active in axoneme and ciliary base. Human ortholog(s) of this gene implicated in spermatogenic failure 83. Orthologous to human DNALI1 (dynein axonemal light intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 158.4), Lung (RPKM 54.1) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Dnali1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (142603132..142611970, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (137318475..137327313, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (143053365..143062203, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene R-spondin 1 Neighboring gene uncharacterized LOC108351029 Neighboring gene G protein nucleolar 2 Neighboring gene Smad nuclear interacting protein 1 Neighboring gene MYST/Esa1-associated factor 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC116176

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dynein heavy chain binding  
    enables dynein heavy chain binding  
    Process Evidence Code Pubs
    involved_in sperm flagellum assembly  
    involved_in sperm flagellum assembly  
    Component Evidence Code Pubs
    located_in 9+2 motile cilium  
    is_active_in axoneme  
    located_in axoneme  
    located_in axoneme  
    is_active_in ciliary base  
    located_in ciliary base  
    located_in cilium  
    located_in cytoplasm  
    located_in dynein axonemal particle  
    part_of dynein complex  
    located_in filopodium  
    located_in motile cilium  
    located_in motile cilium  
    located_in sperm flagellum  
    located_in sperm flagellum  

    General protein information

    Preferred Names
    axonemal dynein light intermediate polypeptide 1
    Names
    dynein, axonemal, light intermediate polypeptide 1
    inner dynein arm light chain, axonemal

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031647.1NP_001026817.1  axonemal dynein light intermediate polypeptide 1

      See identical proteins and their annotated locations for NP_001026817.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099087
      UniProtKB/Swiss-Prot
      Q4FZV3
      UniProtKB/TrEMBL
      A6IS72
      Related
      ENSRNOP00000032193.2, ENSRNOT00000029388.4
      Conserved Domains (1) summary
      pfam10211
      Location:66247
      Ax_dynein_light; Axonemal dynein light chain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      142603132..142611970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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