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    Myo1d myosin ID [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25485, updated on 9-Dec-2024

    Summary

    Official Symbol
    Myo1dprovided by RGD
    Official Full Name
    myosin IDprovided by RGD
    Primary source
    RGD:621321
    See related
    EnsemblRapid:ENSRNOG00000003276 AllianceGenome:RGD:621321
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Myr2; Myr4; Myo1c
    Summary
    Enables several functions, including actin filament binding activity; calcium-dependent protein binding activity; and calmodulin binding activity. Involved in forebrain development. Located in several cellular components, including apical dendrite; axolemma; and basolateral plasma membrane. Part of myosin complex. Orthologous to human MYO1D (myosin ID). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 161.9), Kidney (RPKM 149.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Myo1d in Genome Data Viewer
    Location:
    10q26
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (65986900..66263538, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (65489153..65765812, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (67866939..68142864, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, non-ATPase 11 Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1 like Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1 Neighboring gene uncharacterized LOC134480833 Neighboring gene small nucleolar RNA SNORA26 Neighboring gene transmembrane protein 98 Neighboring gene uncharacterized LOC134480835

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Interactions

    General gene information

    Clone Names

    • MGC93573

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables actin binding  
    enables actin filament binding  
    enables actin filament binding PubMed 
    enables calcium-dependent protein binding PubMed 
    enables calmodulin binding PubMed 
    enables calmodulin binding  
    enables calmodulin binding PubMed 
    enables cytoskeletal motor activity  
    enables microfilament motor activity  
    enables microfilament motor activity PubMed 
    enables protein domain specific binding  
    enables protein domain specific binding  
    Process Evidence Code Pubs
    involved_in actin filament organization  
    involved_in actin filament-based movement  
    involved_in early endosome to recycling endosome transport  
    involved_in endocytosis  
    involved_in forebrain development PubMed 
    involved_in protein transport  
    Items 1 - 20 of 28
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton  
    located_in apical dendrite PubMed 
    located_in axolemma PubMed 
    located_in axon  
    located_in axon  
    located_in basolateral plasma membrane PubMed 
    located_in brush border PubMed 
    located_in brush border  
    located_in brush border  
    located_in cell cortex  
    is_active_in cytoplasm  
    located_in cytoplasmic vesicle PubMed 
    located_in dendrite  
    located_in early endosome  
    located_in endosome  
    is_active_in microvillus  
    located_in myelin sheath PubMed 
    located_in myelin sheath  
    located_in myelin sheath  
    located_in myelin sheath  
    part_of myosin complex PubMed 
    part_of myosin complex  
    located_in neuron projection  
    located_in neuronal cell body PubMed 
    located_in neuronal cell body  
    located_in perikaryon  
    is_active_in plasma membrane  
    located_in plasma membrane raft PubMed 
    Items 1 - 20 of 28

    General protein information

    Preferred Names
    unconventional myosin-Id
    Names
    Unconventional myosin from rat 4 for myosin I heavy chain
    myosin 1C
    myosin IC
    myosin heavy chain myr 4
    myosin-Id
    myosin1C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012983.2NP_037115.2  unconventional myosin-Id

      See identical proteins and their annotated locations for NP_037115.2

      Status: PROVISIONAL

      Source sequence(s)
      BC087027
      UniProtKB/Swiss-Prot
      Q5PQU2, Q63357
      UniProtKB/TrEMBL
      A6HHC1
      Related
      ENSRNOP00000004609.3, ENSRNOT00000004609.6
      Conserved Domains (2) summary
      cd01378
      Location:24682
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:803996
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      65986900..66263538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268469.1XP_063124539.1  unconventional myosin-Id isoform X1

      UniProtKB/TrEMBL
      A0A8I6GJN3
      Related
      ENSRNOP00000091463.1, ENSRNOT00000108255.2
    2. XM_063268468.1XP_063124538.1  unconventional myosin-Id isoform X1

      UniProtKB/TrEMBL
      A0A8I6GJN3
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