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    Slc25a36 solute carrier family 25 member 36 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501039, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc25a36provided by RGD
    Official Full Name
    solute carrier family 25 member 36provided by RGD
    Primary source
    RGD:1591928
    See related
    EnsemblRapid:ENSRNOG00000078852 AllianceGenome:RGD:1591928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Predicted to be involved in mitochondrial genome maintenance; pyrimidine nucleotide import into mitochondrion; and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 8. Orthologous to human SLC25A36 (solute carrier family 25 member 36). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 545.6), Lung (RPKM 416.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc25a36 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (106539355..106573240, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (97659848..97693735, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (104962569..104995935, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480089 Neighboring gene uncharacterized LOC134480218 Neighboring gene BCL2 associated X, apoptosis regulator, pseudogene 1 Neighboring gene 40S ribosomal protein S17-like Neighboring gene tripartite motif-containing 42

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    is_active_in mitochondrion  
    located_in mitochondrion  

    General protein information

    Preferred Names
    solute carrier family 25 member 36
    Names
    solute carrier family 25 (pyrimidine nucleotide carrier ), member 36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427729.1NP_001414658.1  solute carrier family 25 member 36

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JV03, D4ACN9
      Related
      ENSRNOP00000033519.3, ENSRNOT00000037120.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      106539355..106573240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766577.4XP_008764799.1  solute carrier family 25 member 36 isoform X1

      See identical proteins and their annotated locations for XP_008764799.1

      UniProtKB/TrEMBL
      A0A0G2JV03
      Related
      ENSRNOP00000109110.1, ENSRNOT00000131210.1
      Conserved Domains (1) summary
      pfam00153
      Location:88180
      Mito_carr; Mitochondrial carrier protein
    2. XM_063265997.1XP_063122067.1  solute carrier family 25 member 36 isoform X2

    3. XM_063265996.1XP_063122066.1  solute carrier family 25 member 36 isoform X2

    4. XM_039082574.2XP_038938502.1  solute carrier family 25 member 36 isoform X2

      Conserved Domains (1) summary
      pfam00153
      Location:30105
      Mito_carr; Mitochondrial carrier protein
    5. XM_039082571.2XP_038938499.1  solute carrier family 25 member 36 isoform X2

      Conserved Domains (1) summary
      pfam00153
      Location:30105
      Mito_carr; Mitochondrial carrier protein
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