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    Rbp1 retinol binding protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25056, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rbp1provided by RGD
    Official Full Name
    retinol binding protein 1provided by RGD
    Primary source
    RGD:3543
    See related
    AllianceGenome:RGD:3543
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables retinol binding activity. Involved in response to benzoic acid; response to retinoic acid; and retinoid metabolic process. Located in cell body. Human ortholog(s) of this gene implicated in multiple myeloma. Orthologous to human RBP1 (retinol binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 917.6), Kidney (RPKM 594.2) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Rbp1 in Genome Data Viewer
    Location:
    8q31
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (107904589..107926109)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (99025218..99046740)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (106449321..106470842)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene calsyntenin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene nicotinamide nucleotide adenylyltransferase 3 Neighboring gene NME/NM23 nucleoside diphosphate kinase 2, pseudogene 8 Neighboring gene retinol binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables all-trans-retinol binding  
    enables all-trans-retinol binding  
    enables all-trans-retinol binding  
    enables fatty acid binding  
    enables retinal binding  
    enables retinol binding PubMed 
    Component Evidence Code Pubs
    located_in cell body PubMed 
    is_active_in cytosol  
    located_in cytosol  
    located_in lipid droplet  
    located_in lipid droplet  
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  

    General protein information

    Preferred Names
    retinol-binding protein 1
    Names
    CRBP
    CRBP-I
    cellular retinol-binding protein I
    retinol binding protein 1, cellular
    NP_036865.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012733.5NP_036865.1  retinol-binding protein 1

      See identical proteins and their annotated locations for NP_036865.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      P02696
      Conserved Domains (1) summary
      cd19462
      Location:4134
      CRBP1; cellular retinol-binding protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      107904589..107926109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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