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    Kmt2c lysine methyltransferase 2C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502710, updated on 27-Dec-2024

    Summary

    Official Symbol
    Kmt2cprovided by RGD
    Official Full Name
    lysine methyltransferase 2Cprovided by RGD
    Primary source
    RGD:1587205
    See related
    EnsemblRapid:ENSRNOG00000061080 AllianceGenome:RGD:1587205
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable histone H3K4 methyltransferase activity and transcription coactivator activity. Involved in response to electrical stimulus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of MLL3/4 complex. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in Kleefstra syndrome 2; carcinoma (multiple); and stomach cancer. Orthologous to human KMT2C (lysine methyltransferase 2C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 248.0), Lung (RPKM 176.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Kmt2c in Genome Data Viewer
    Location:
    4q11
    Exon count:
    66
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (10353698..10755965)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (9620638..9834787)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (82506..109986) , (6083650..6294413)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486540 Neighboring gene chaperonin containing TCP1 subunit 8 like 2 Neighboring gene microtubule-associated protein 1 light chain 3 beta, pseudogene 2 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene ribosomal protein L30, pseudogene 8 Neighboring gene polypeptide N-acetylgalactosaminyltransferase-like 5 Neighboring gene calcineurin B homologous protein 1-like Neighboring gene hypothetical LOC100359776 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 2 Neighboring gene uncharacterized LOC102554253 Neighboring gene uncharacterized LOC102554193

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone H3K4 methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of MLL3/4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of MLL3/4 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase 2C; similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3)
    Names
    lysine (K)-specific methyltransferase 2C
    myeloid/lymphoid or mixed-lineage leukemia 3-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      10353698..10755965
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108963.2XP_038964891.1  histone-lysine N-methyltransferase 2C isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4Z1, A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44944598
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48505002
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46434694
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:47004784
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    2. XM_063286806.1XP_063142876.1  histone-lysine N-methyltransferase 2C isoform X20

      UniProtKB/TrEMBL
      A0A8I6A900
    3. XM_039108964.2XP_038964892.1  histone-lysine N-methyltransferase 2C isoform X2

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16581711
      HMG; high mobility group
      PHA03247
      Location:19002380
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26932954
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:342387
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:465516
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:389434
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:246329
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44934597
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48495001
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32013283
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24382691
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46424693
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46994783
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9471003
      PHD_SF; PHD finger superfamily
    4. XM_063286800.1XP_063142870.1  histone-lysine N-methyltransferase 2C isoform X12

      UniProtKB/TrEMBL
      A0A8I6A900, A0A8I6G4C0
    5. XM_063286805.1XP_063142875.1  histone-lysine N-methyltransferase 2C isoform X20

      UniProtKB/TrEMBL
      A0A8I6A900
    6. XM_039108982.2XP_038964910.1  histone-lysine N-methyltransferase 2C isoform X27

      Conserved Domains (12) summary
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    7. XM_039108981.2XP_038964909.1  histone-lysine N-methyltransferase 2C isoform X26

      Conserved Domains (13) summary
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    8. XM_039108969.2XP_038964897.1  histone-lysine N-methyltransferase 2C isoform X7

      UniProtKB/TrEMBL
      A0A8I6A900
      Related
      ENSRNOP00000107839.1, ENSRNOT00000157963.1
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44944598
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48464998
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46434694
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:47004784
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    9. XM_039108966.2XP_038964894.1  histone-lysine N-methyltransferase 2C isoform X5

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44934597
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48495001
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46424693
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46994783
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    10. XM_039108971.2XP_038964899.1  histone-lysine N-methyltransferase 2C isoform X14

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44704574
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48264978
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46194670
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46764760
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    11. XM_063286803.1XP_063142873.1  histone-lysine N-methyltransferase 2C isoform X16

      UniProtKB/TrEMBL
      A0A8I6A900
    12. XM_039108965.2XP_038964893.1  histone-lysine N-methyltransferase 2C isoform X3

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44934597
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48495001
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46424693
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46994783
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    13. XM_063286798.1XP_063142868.1  histone-lysine N-methyltransferase 2C isoform X9

      UniProtKB/TrEMBL
      A0A8I6A900
    14. XM_063286802.1XP_063142872.1  histone-lysine N-methyltransferase 2C isoform X15

      UniProtKB/TrEMBL
      A0A8I6A900
    15. XM_039108978.2XP_038964906.1  histone-lysine N-methyltransferase 2C isoform X22

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (18) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43684472
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05109
      Location:36543856
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd19171
      Location:47244876
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:45174568
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45744658
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    16. XM_063286809.1XP_063142879.1  histone-lysine N-methyltransferase 2C isoform X24

      UniProtKB/TrEMBL
      A0A8I6A900
    17. XM_063286808.1XP_063142878.1  histone-lysine N-methyltransferase 2C isoform X23

      UniProtKB/TrEMBL
      A0A8I6A900
    18. XM_039108979.2XP_038964907.1  histone-lysine N-methyltransferase 2C isoform X25

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16591712
      HMG; high mobility group
      PHA03247
      Location:19012381
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26942955
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43444448
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:47004852
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32023284
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24392692
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:44934544
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45504634
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    19. XM_008762670.4XP_008760892.2  histone-lysine N-methyltransferase 2C isoform X11

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16431696
      HMG; high mobility group
      PHA03247
      Location:18852365
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26782939
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44784582
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48344986
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:31863268
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24232676
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46274678
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46844768
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    20. XM_063286810.1XP_063142880.1  histone-lysine N-methyltransferase 2C isoform X28

      UniProtKB/TrEMBL
      A0A8I6A900
      Related
      ENSRNOP00000089164.2, ENSRNOT00000101551.2
    21. XM_039108973.2XP_038964901.1  histone-lysine N-methyltransferase 2C isoform X19

      UniProtKB/TrEMBL
      A0A8I6A825, A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16081661
      HMG; high mobility group
      PHA03247
      Location:18502330
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26432904
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10801102
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10051051
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10821132
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44434547
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:47994951
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:31513233
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:23882641
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:45924643
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46494733
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9481004
      PHD_SF; PHD finger superfamily
    22. XM_039108972.2XP_038964900.1  histone-lysine N-methyltransferase 2C isoform X17

      UniProtKB/TrEMBL
      A0A8I6A900
      Related
      ENSRNOP00000086031.2, ENSRNOT00000108916.2
      Conserved Domains (17) summary
      PHA03247
      Location:18612341
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26542915
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10401062
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9651011
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10421092
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44544558
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48104962
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:31623244
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:23992652
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46034654
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46604744
      FYRC; F/Y rich C-terminus
      cl00082
      Location:16211672
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:908964
      PHD_SF; PHD finger superfamily
    23. XM_063286807.1XP_063142877.1  histone-lysine N-methyltransferase 2C isoform X21

      UniProtKB/TrEMBL
      A0A8I6A900
      Related
      ENSRNOP00000089859.2, ENSRNOT00000093625.3
    24. XM_063286811.1XP_063142881.1  histone-lysine N-methyltransferase 2C isoform X29

      UniProtKB/TrEMBL
      A0A8I6A900
      Related
      ENSRNOP00000078989.2, ENSRNOT00000103015.2
    25. XM_039108967.2XP_038964895.1  histone-lysine N-methyltransferase 2C isoform X4

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      smart00398
      Location:16581711
      HMG; high mobility group
      PHA03247
      Location:19002380
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26932954
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44934597
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48495001
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:32013283
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24382691
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46424693
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46994783
      FYRC; F/Y rich C-terminus
      cl22851
      Location:9471003
      PHD_SF; PHD finger superfamily
    26. XM_063286804.1XP_063142874.1  histone-lysine N-methyltransferase 2C isoform X18

      UniProtKB/TrEMBL
      A0A8I6A900
    27. XM_063286797.1XP_063142867.1  histone-lysine N-methyltransferase 2C isoform X6

      UniProtKB/TrEMBL
      A0A8I6A900
    28. XM_063286801.1XP_063142871.1  histone-lysine N-methyltransferase 2C isoform X13

      UniProtKB/TrEMBL
      A0A8I6A900
    29. XM_039108968.2XP_038964896.1  histone-lysine N-methyltransferase 2C isoform X8

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      PHA03247
      Location:18972377
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26902951
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10761098
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:339384
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:462513
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10011047
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:386431
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10781128
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:243326
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44904594
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48464998
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:31983280
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24352688
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46394690
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46964780
      FYRC; F/Y rich C-terminus
      cl00082
      Location:16571708
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:9441000
      PHD_SF; PHD finger superfamily
    30. XM_039108970.2XP_038964898.1  histone-lysine N-methyltransferase 2C isoform X10

      UniProtKB/TrEMBL
      A0A8I6A900
      Conserved Domains (17) summary
      PHA03247
      Location:18962376
      PHA03247; large tegument protein UL36; Provisional
      COG5271
      Location:26892950
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:10751097
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:338383
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:461512
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10001046
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:385430
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10771127
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:242325
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44894593
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd19171
      Location:48454997
      SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
      pfam01576
      Location:31973279
      Myosin_tail_1; Myosin tail
      pfam03154
      Location:24342687
      Atrophin-1; Atrophin-1 family
      pfam05964
      Location:46384689
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46954779
      FYRC; F/Y rich C-terminus
      cl00082
      Location:16561707
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:943999
      PHD_SF; PHD finger superfamily

    RNA

    1. XR_010065729.1 RNA Sequence

    2. XR_005504105.2 RNA Sequence

    3. XR_005504104.2 RNA Sequence