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    Ankrd35 ankyrin repeat domain 35 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 365881, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ankrd35provided by RGD
    Official Full Name
    ankyrin repeat domain 35provided by RGD
    Primary source
    RGD:1305527
    See related
    EnsemblRapid:ENSRNOG00000025108 AllianceGenome:RGD:1305527
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305527
    Summary
    Predicted to enable actin binding activity. Orthologous to human ANKRD35 (ankyrin repeat domain 35). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 33.5), Brain (RPKM 15.0) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd35 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (186895896..186915903)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (184207076..184227063)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (198797136..198817144)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene RNA, U2 small nuclear 64 Neighboring gene integrin subunit alpha 10 Neighboring gene uncharacterized LOC120100888 Neighboring gene protein inhibitor of activated STAT, 3 Neighboring gene nudix hydrolase 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain 35; ankyrin repeat domain-containing protein 35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001433210.1 → NP_001420139.1  ankyrin repeat domain 35

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6K387

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      186895896..186915903
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_345258.10 → XP_345259.5  ankyrin repeat domain-containing protein 35 isoform X1

      Related
      ENSRNOP00000053068.5, ENSRNOT00000056225.6
      Conserved Domains (4) summary
      cd00204
      Location:81 → 206
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:58 → 150
      Ank_2; Ankyrin repeats (3 copies)
      pfam14662
      Location:740 → 952
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      sd00045
      Location:53 → 84
      ANK; ANK repeat [structural motif]

    2. XM_063282738.1 → XP_063138808.1  ankyrin repeat domain-containing protein 35 isoform X1

      UniProtKB/TrEMBL
      A6K387

    3. XM_063282739.1 → XP_063138809.1  ankyrin repeat domain-containing protein 35 isoform X2

      UniProtKB/TrEMBL
      A6K387, D3ZHR4

    4. XM_006232996.5 → XP_006233058.1  ankyrin repeat domain-containing protein 35 isoform X2

      See identical proteins and their annotated locations for XP_006233058.1

      UniProtKB/TrEMBL
      A6K387, D3ZHR4
      Conserved Domains (4) summary
      cd00204
      Location:30 → 155
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:7 → 99
      Ank_2; Ankyrin repeats (3 copies)
      pfam14662
      Location:689 → 901
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      sd00045
      Location:35 → 66
      ANK; ANK repeat [structural motif]

    5. XM_063282740.1 → XP_063138810.1  ankyrin repeat domain-containing protein 35 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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