Cep162 centrosomal protein 162 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cep162provided by RGD
Official Full Name: centrosomal protein 162provided by RGD
Primary source: RGD:1307365
See related: EnsemblRapid:ENSRNOG00000010608 AllianceGenome:RGD:1307365
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Qn1; RGD1307365
Summary: Predicted to be involved in cilium assembly. Predicted to be located in centrosome and cytosol. Predicted to be active in microtubule cytoskeleton and nucleoplasm. Orthologous to human CEP162 (centrosomal protein 162). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 73.8), Kidney (RPKM 45.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q31

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (97029677..97088243, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (88149726..88208249, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (94863282..94921917, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cell projection organization	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in axonemal microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
is_active_in centriolar satellite	IBA Inferred from Biological aspect of Ancestor more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	IEA Inferred from Electronic Annotation more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in spindle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: centrosomal protein of 162 kDa

Names: protein QN1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277060.1 → NP_001263989.1 centrosomal protein of 162 kDa

See identical proteins and their annotated locations for NP_001263989.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/Swiss-Prot

Q4KLH6

Conserved Domains (1) summary

COG1196
Location:613 → 1300

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

97029677..97088243 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006243475.5 → XP_006243537.1 centrosomal protein of 162 kDa isoform X1

See identical proteins and their annotated locations for XP_006243537.1

UniProtKB/Swiss-Prot

Q4KLH6

Related

ENSRNOP00000014165.5, ENSRNOT00000014165.8

Conserved Domains (1) summary

COG1196
Location:613 → 1300

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_006243476.5 → XP_006243538.1 centrosomal protein of 162 kDa isoform X2

UniProtKB/TrEMBL

A0A8L2R9X6

Related

ENSRNOP00000075055.2, ENSRNOT00000083934.3

Conserved Domains (1) summary

COG1196
Location:549 → 1236

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_008766441.3 → XP_008764663.1 centrosomal protein of 162 kDa isoform X3

UniProtKB/TrEMBL

A6I1X4

Conserved Domains (1) summary

COG1196
Location:393 → 1080

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_063265193.1 → XP_063121263.1 centrosomal protein of 162 kDa isoform X4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001037771.1: Suppressed sequence

Description

NM_001037771.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.