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    Cavin3 caveolae associated protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 85332, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cavin3provided by RGD
    Official Full Name
    caveolae associated protein 3provided by RGD
    Primary source
    RGD:628755
    See related
    EnsemblRapid:ENSRNOG00000017914 AllianceGenome:RGD:628755
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Srbc; DIG-2; Prkcdbp
    Summary
    Enables protein kinase C binding activity. Predicted to be involved in circadian regulation of gene expression. Predicted to act upstream of or within cortical actin cytoskeleton organization; negative regulation of fermentation; and regulation of intracellular signal transduction. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Predicted to be active in caveola and cytoplasm. Orthologous to human CAVIN3 (caveolae associated protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 571.5), Liver (RPKM 409.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cavin3 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (169238384..169239973, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (159826549..159828138, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (170317099..170318688, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel subunit alpha 4 Neighboring gene FHF complex subunit HOOK interacting protein 1B Neighboring gene uncharacterized LOC108349007 Neighboring gene cholecystokinin B receptor Neighboring gene uncharacterized LOC134483765 Neighboring gene sphingomyelin phosphodiesterase 1

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein kinase C binding  
    enables protein kinase C binding PubMed 
    enables protein kinase C binding  
    enables protein kinase C binding  
    Component Evidence Code Pubs
    is_active_in caveola  
    located_in caveola  
    located_in caveola  
    located_in caveola  
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in cytoplasm  
    located_in cytosol  
    part_of protein-containing complex  
    part_of protein-containing complex  

    General protein information

    Preferred Names
    caveolae-associated protein 3
    Names
    D3T-inducible gene 2 protein
    PKC-delta binding protein
    cavin-3
    dithiolethione-inducible gene 2 protein
    dithiolethione-inducible gene-2
    protein kinase C, delta binding protein
    sdr-elated gene product that binds to c-kinase
    serum deprivation response factor-related gene product that binds to C-kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134449.1NP_604444.1  caveolae-associated protein 3

      See identical proteins and their annotated locations for NP_604444.1

      Status: PROVISIONAL

      Source sequence(s)
      D85435
      UniProtKB/Swiss-Prot
      P97585, Q9Z1H9
      UniProtKB/TrEMBL
      A0A8L2QDP3, A6I7I4
      Related
      ENSRNOP00000024119.3, ENSRNOT00000024119.6
      Conserved Domains (1) summary
      pfam15237
      Location:20194
      PTRF_SDPR; PTRF/SDPR family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      169238384..169239973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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