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    Cntn5 contactin 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 114589, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cntn5provided by RGD
    Official Full Name
    contactin 5provided by RGD
    Primary source
    RGD:621302
    See related
    EnsemblRapid:ENSRNOG00000007038 AllianceGenome:RGD:621302
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Nb-2
    Summary
    Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in cell-cell adhesion and nervous system development. Predicted to act upstream of or within sensory perception of sound. Predicted to be located in side of membrane. Predicted to be active in GABA-ergic synapse; axon; and presynaptic membrane. Orthologous to human CNTN5 (contactin 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 39.3) See more
    Orthologs
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    Genomic context

    See Cntn5 in Genome Data Viewer
    Location:
    8q11
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (15017424..16249418, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (6735715..7967727, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (7812371..9033962, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) 60 Neighboring gene mitochondrial pyruvate carrier 1-like, pseudogene 2 Neighboring gene TATA element modulatory factor-like Neighboring gene uncharacterized LOC102548563 Neighboring gene prohibitin 1, pseudogene 18 Neighboring gene uncharacterized LOC134479992 Neighboring gene eukaryotic translation initiation factor 1 pseudogene Neighboring gene Serine/threonine-protein kinase Sgk1, pseudogene 1 Neighboring gene uncharacterized LOC120094309 Neighboring gene nucleophosmin 1, pseudogene 17 Neighboring gene heterogeneous nuclear ribonucleoprotein L, pseudogene 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in axon guidance  
    involved_in brain development  
    involved_in cell adhesion  
    involved_in cell adhesion PubMed 
    involved_in cell-cell adhesion  
    involved_in presynapse assembly  
    involved_in presynapse assembly  
    involved_in sensory perception of sound  
    acts_upstream_of_or_within sensory perception of sound  
    Component Evidence Code Pubs
    located_in GABA-ergic synapse  
    is_active_in GABA-ergic synapse  
    is_active_in axon  
    is_active_in plasma membrane  
    located_in plasma membrane  
    located_in presynaptic membrane  
    is_active_in presynaptic membrane  
    located_in side of membrane  

    General protein information

    Preferred Names
    contactin-5
    Names
    neural recognition molecule NB-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053746.1NP_446198.1  contactin-5 precursor

      See identical proteins and their annotated locations for NP_446198.1

      Status: PROVISIONAL

      Source sequence(s)
      D87212
      UniProtKB/Swiss-Prot
      P97527
      UniProtKB/TrEMBL
      A6JN62, F1M173
      Related
      ENSRNOP00000009418.8, ENSRNOT00000009418.9
      Conserved Domains (5) summary
      cd04969
      Location:496568
      Ig5_Contactin_like; Fifth Ig domain of contactin
      smart00410
      Location:205278
      IG_like; Immunoglobulin like
      cd00063
      Location:671768
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:480568
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:98191
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      15017424..16249418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017595409.2XP_017450898.1  contactin-5 isoform X1

      UniProtKB/Swiss-Prot
      P97527
      UniProtKB/TrEMBL
      A6JN62, F1M173
    2. XM_017595411.3XP_017450900.1  contactin-5 isoform X2

      UniProtKB/TrEMBL
      F1M173
      Related
      ENSRNOP00000109036.1, ENSRNOT00000162546.1
    3. XM_017595408.3XP_017450897.1  contactin-5 isoform X1

      UniProtKB/Swiss-Prot
      P97527
      UniProtKB/TrEMBL
      A6JN62, F1M173
    4. XM_039080701.2XP_038936629.1  contactin-5 isoform X3

      Conserved Domains (3) summary
      cd00096
      Location:100104
      Ig; Ig strand A [structural motif]
      cd04969
      Location:480568
      Ig5_Contactin; Fifth immunoglobulin (Ig) domain of contactin
      cl11960
      Location:98193
      Ig; Immunoglobulin domain
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