Jpt2 Jupiter microtubule associated homolog 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Jpt2provided by RGD
Official Full Name: Jupiter microtubule associated homolog 2provided by RGD
Primary source: RGD:1305117
See related: EnsemblRapid:ENSRNOG00000024635 AllianceGenome:RGD:1305117
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hn1l; RGD1305117
Summary: Predicted to be involved in endocytosis involved in viral entry into host cell and regulation of calcium-mediated signaling. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Orthologous to human JPT2 (Jupiter microtubule associated homolog 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 138.7), Liver (RPKM 105.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (14467652..14487769, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (13963135..13983212, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (14304108..14324170, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HN1L/JPT2: A signaling protein that connects NAADP generation to Ca(2+) microdomain formation.
Title: HN1L/JPT2: A signaling protein that connects NAADP generation to Ca(2+) microdomain formation.

Submit: New GeneRIF Correction

General gene information

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Markers

AI790734 (e-PCR)
- UniSTS:164621

RH135174 (e-PCR)
- UniSTS:218451

RH140063 (e-PCR)
- UniSTS:222144

AI060075 (e-PCR)
- UniSTS:248816

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in endocytosis involved in viral entry into host cell	ISO Inferred from Sequence Orthology more info
involved_in regulation of calcium-mediated signaling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: jupiter microtubule associated homolog 2

Names: HN1-like protein; hematological and neurological expressed 1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.