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    Tvp23a trans-golgi network vesicle protein 23 homolog A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360467, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tvp23aprovided by RGD
    Official Full Name
    trans-golgi network vesicle protein 23 homolog Aprovided by RGD
    Primary source
    RGD:1566405
    See related
    EnsemblRapid:ENSRNOG00000079813 AllianceGenome:RGD:1566405
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam18a; RGD1566405
    Summary
    Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be active in Golgi membrane. Orthologous to human TVP23A (trans-golgi network vesicle protein 23 homolog A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 50.5), Thymus (RPKM 21.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tvp23a in Genome Data Viewer
    Location:
    10q11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5734100..5770002)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (5227198..5263185)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (5300319..5335160)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta, pseudogene 1 Neighboring gene CCHC-type zinc finger, nucleic acid binding protein, pseudogene 2 Neighboring gene uncharacterized LOC134480647 Neighboring gene NUBP iron-sulfur cluster assembly factor 1 Neighboring gene uncharacterized LOC102553451 Neighboring gene tektin 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Golgi apparatus membrane protein TVP23 homolog A
    Names
    family with sequence similarity 18, member A
    trans-golgi network vesicle protein 23A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108263.3NP_001101733.1  Golgi apparatus membrane protein TVP23 homolog A isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6K4K0
      Conserved Domains (1) summary
      pfam05832
      Location:39180
      DUF846; Eukaryotic protein of unknown function (DUF846)
    2. NM_001393687.2NP_001380616.1  Golgi apparatus membrane protein TVP23 homolog A isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      Related
      ENSRNOP00000110455.1, ENSRNOT00000145927.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      5734100..5770002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)