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    Cntnap5bl1 contactin associated protein family member 5B like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304725, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cntnap5bl1provided by RGD
    Official Full Name
    contactin associated protein family member 5B like 1provided by RGD
    Primary source
    RGD:1592077
    See related
    EnsemblRapid:ENSRNOG00000066325 AllianceGenome:RGD:1592077
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Caspr5-2
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in basement membrane and membrane. Orthologous to human CNTNAP5 (contactin associated protein family member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 31.3) See more
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    Genomic context

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    See Cntnap5bl1 in Genome Data Viewer
    Location:
    13p13
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (12378466..13383261, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (11853761..12864307, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (14373645..15396535, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 715, pseudogene 2 Neighboring gene ubiquitin C like 1 Neighboring gene cellular tumor antigen p53-like Neighboring gene small nucleolar RNA SNORA17 Neighboring gene eukaryotic translation initiation factor 4A1, pseudogene 1 Neighboring gene transfer RNA proline (anticodon GGG) 8 Neighboring gene uncharacterized LOC134481469

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. New members of the neurexin superfamily: multiple rodent homologues of the human CASPR5 gene. Traut W, et al. Mamm Genome, 2006 Jul. PMID 16845472

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    similar to contactin associated protein-like 5 isoform 1; similar to contactin associated protein-like 5
    Names
    contactin associated protein-like 5-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001329899.4 → NP_001316828.2  similar to contactin associated protein-like 5 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/Swiss-Prot
      Q0V8T5
      UniProtKB/TrEMBL
      A0A8I5Y093
      Related
      ENSRNOP00000076652.1, ENSRNOT00000106987.2
      Conserved Domains (5) summary
      smart00282
      Location:802 → 926
      LamG; Laminin G domain
      cd00054
      Location:542 → 583
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00057
      Location:44 → 173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:180 → 336
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam02210
      Location:396 → 522
      Laminin_G_2; Laminin G domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      12378466..13383261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063272228.1 → XP_063128298.1  similar to contactin associated protein-like 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A9S8

    2. XM_063272229.1 → XP_063128299.1  similar to contactin associated protein-like 5 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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