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    Dnaaf8 dynein axonemal assembly factor 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360479, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnaaf8provided by RGD
    Official Full Name
    dynein axonemal assembly factor 8provided by RGD
    Primary source
    RGD:1359596
    See related
    EnsemblRapid:ENSRNOG00000028075 AllianceGenome:RGD:1359596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Daap1
    Summary
    Predicted to enable dynein complex binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be located in cytoplasm. Predicted to be active in dynein axonemal particle. Orthologous to human DNAAF8 (dynein axonemal assembly factor 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 167.9), Kidney (RPKM 16.0) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dnaaf8 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (11107988..11121475, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (10600747..10614891, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (10794441..10808665, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 22 Neighboring gene septin 12 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 3 Neighboring gene nudix hydrolase 16 like 1 Neighboring gene mahogunin ring finger 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dynein complex binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dynein complex binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in outer dynein arm assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in dynein axonemal particle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in dynein axonemal particle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dynein axonemal particle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dynein axonemal particle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    dynein axonemal assembly factor 8
    Names
    dynein axonemal-associated protein 1
    uncharacterized protein C16orf71 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014115.1 → NP_001014137.1  dynein axonemal assembly factor 8

      See identical proteins and their annotated locations for NP_001014137.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083674
      UniProtKB/Swiss-Prot
      Q5XIK6
      UniProtKB/TrEMBL
      A0A8L2R8P6, A6K4Q0
      Related
      ENSRNOP00000037410.4, ENSRNOT00000036954.6
      Conserved Domains (1) summary
      pfam15773
      Location:15 → 480
      DUF4701; Domain of unknown function (DUF4701)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      11107988..11121475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269293.1 → XP_063125363.1  dynein axonemal assembly factor 8 isoform X1

      UniProtKB/Swiss-Prot
      Q5XIK6
      UniProtKB/TrEMBL
      A0A8L2R8P6, A6K4Q0

    2. XM_017597364.3 → XP_017452853.1  dynein axonemal assembly factor 8 isoform X1

      UniProtKB/Swiss-Prot
      Q5XIK6
      UniProtKB/TrEMBL
      A0A8L2R8P6, A6K4Q0
      Conserved Domains (1) summary
      pfam15773
      Location:15 → 480
      DUF4701; Domain of unknown function (DUF4701)

    3. XM_063269292.1 → XP_063125362.1  dynein axonemal assembly factor 8 isoform X1

      UniProtKB/Swiss-Prot
      Q5XIK6
      UniProtKB/TrEMBL
      A0A8L2R8P6, A6K4Q0

    4. XM_006245807.5 → XP_006245869.1  dynein axonemal assembly factor 8 isoform X1

      See identical proteins and their annotated locations for XP_006245869.1

      UniProtKB/Swiss-Prot
      Q5XIK6
      UniProtKB/TrEMBL
      A0A8L2R8P6, A6K4Q0
      Conserved Domains (1) summary
      pfam15773
      Location:15 → 480
      DUF4701; Domain of unknown function (DUF4701)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIK6.1 GenPept UniProtKB/Swiss-Prot:Q5XIK6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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