U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293453, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufab1provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit AB1provided by RGD
    Primary source
    RGD:1305619
    See related
    EnsemblRapid:ENSRNOG00000018129 AllianceGenome:RGD:1305619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acyl binding activity; acyl carrier activity; and mitochondrial large ribosomal subunit binding activity. Predicted to be involved in [2Fe-2S] cluster assembly; mitochondrial respiratory chain complex I assembly; and protein lipoylation. Predicted to be located in mitochondrial inner membrane and nucleoplasm. Predicted to be part of mitochondrial [2Fe-2S] assembly complex and respiratory chain complex I. Predicted to be active in mitochondrion. Orthologous to human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 520.3), Muscle (RPKM 354.6) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ndufab1 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (186075933..186091843, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (176644696..176658131, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (192044209..192057644, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial Neighboring gene ubiquitin family domain containing 1 Neighboring gene partner and localizer of BRCA2 Neighboring gene dynactin subunit 5

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acyl binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acyl carrier activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mitochondrial large ribosomal subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein lipoylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial [2Fe-2S] assembly complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    acyl carrier protein, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106294.1NP_001099764.1  acyl carrier protein, mitochondrial

      See identical proteins and their annotated locations for NP_001099764.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473956
      UniProtKB/TrEMBL
      A6I8V9, D3ZF13
      Related
      ENSRNOP00000024471.4, ENSRNOT00000024471.9
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      186075933..186091843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006230188.2XP_006230250.1  acyl carrier protein, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006230250.1

      UniProtKB/TrEMBL
      A6I8V9, D3ZF13
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site