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    Nxpe5l3 neurexophilin and PC-esterase domain family, member 5 like 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498165, updated on 17-Aug-2024

    Summary

    Official Symbol
    Nxpe5l3provided by RGD
    Official Full Name
    neurexophilin and PC-esterase domain family, member 5 like 3provided by RGD
    Primary source
    RGD:1562319
    See related
    AllianceGenome:RGD:1562319
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562319; RGD1564217
    Expression
    Biased expression in Lung (RPKM 17.0), Heart (RPKM 14.1) and 9 other tissues See more
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    Genomic context

    See Nxpe5l3 in Genome Data Viewer
    Location:
    12q11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (22351917..22367016)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (17238311..17252723)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (19561408..19567858)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551138 Neighboring gene neurexophilin and PC-esterase domain family, member 5-like 1 Neighboring gene NXPE family member 3-like Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 Neighboring gene trafficking protein particle complex subunit 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    NXPE family member 3-like; similar to family with sequence similarity 55, member C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      22351917..22367016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090102.2XP_038946030.1  NXPE family member 3-like

      UniProtKB/TrEMBL
      F1M0C7
      Conserved Domains (2) summary
      pfam06312
      Location:117257
      Neurexophilin
      cl01053
      Location:446523
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...